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FAP+ activated fibroblasts are detectable in the microenvironment of endometriosis and correlate with stroma composition and infiltrating CD8+ and CD68+ cells.

Do activated fibroblasts expressing fibroblast activation protein-α (FAP) - which is traceable in positron emission topography/computed topography (PET/CT) - play a role in the microenvironment of endometriosis?

Published: Jan. 24, 2025, midnight
Identification of potential druggable targets for endometriosis through Mendelian randomization analysis.

Endometriosis (EM) is a widely recognized disorder in gynecological endocrinology. Although hormonal therapies are frequently employed for EM, their side effects and outcome limitations underscore the need to explore the …

Published: Jan. 22, 2025, midnight
GSK gets European Commission nod for expanded use of Jemperli in endometrial cancer - Medical Dialogues

GSK gets European Commission nod for expanded use of Jemperli in endometrial cancer Medical Dialogues

Published: Jan. 21, 2025, 8 a.m.
European Commission expands Jemperli plus chemotherapy approval for endometrial cancer - Indian Pharma Post

European Commission expands Jemperli plus chemotherapy approval for endometrial cancer Indian Pharma Post

Published: Jan. 21, 2025, 4:36 a.m.
Standardized measurement of the piriformis muscle and the proximal portion of the sacral nerve roots using transvaginal ultrasound.

To identify the sonomorphological appearance and to measure the thickness of the piriformis muscle (PM) and the proximal portion of the sacral nerve roots S1-S3 in healthy premenopausal women.

Published: Jan. 21, 2025, midnight
Neutrophils initiate pro-inflammatory immune responses in early endometriosis lesion development.

Endometriosis is a chronic gynecological disease that affects 1 in 10 reproductive-aged women. Most studies investigate established disease; however, the initiation and early events in endometriotic lesion development remain poorly …

Published: Jan. 21, 2025, midnight
Ovarian Endometrioma Disrupts Oocyte-Cumulus Communication and Mitochondrial Function, With Melatonin Mitigating the Effects.

Ovarian endometrioma (OEM), a particularly severe form of endometriosis, is an oestrogen-dependent condition often associated with pain and infertility. The mechanisms by which OEM impairs fertility, particularly through its direct …

Published: Jan. 21, 2025, midnight
Mum discovers 16 fibroids following years of misdiagnosed menstrual pain - Surrey Live

Mum discovers 16 fibroids following years of misdiagnosed menstrual pain Surrey Live

Published: Jan. 20, 2025, 2:32 a.m.
A cRGD-modified liposome for targeted delivery of artesunate to inhibit angiogenesis in endometriosis.

Currently, hormonal therapy for endometriosis faces challenges in achieving a balance between treatment and preserving the chance of pregnancy. Therefore, the development of non-hormonal therapy holds significant clinical importance. Angiogenesis …

Published: Jan. 20, 2025, midnight
Doctors said she was having a miscarriage – and she didn’t know she was pregnant - Live Action

Doctors said she was having a miscarriage – and she didn’t know she was pregnant Live Action

Published: Jan. 19, 2025, 3:30 p.m.
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