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Dysregulation of Key Biological Processes in Endometriosis Pathophysiology.

Endometriosis is a typical disorder affecting the female reproductive system and is characterized by the presence of tissue resembling the endometrium both within and beyond the pelvic cavity. Unfortunately, the …

Published: Sept. 18, 2025, midnight
Tolerability and Shared Decision-Making in the Hormonal Management of Endometriosis-Associated Pain.

Background: The management of endometriosis-associated pain has traditionally focused on analgesic efficacy. However, with high-level evidence demonstrating therapeutic equivalence among principal hormonal classes, the paradigm has shifted towards a patient-centred …

Published: Sept. 18, 2025, midnight
Balancing Decidualization, Autophagy, and Cellular Senescence for Reproductive Success in Endometriosis Biology.

Endometriosis is a chronic disease characterized by the ectopic presence of endometrial cells that evade apoptosis and survive and proliferate under harsh environmental conditions. It is closely associated with infertility …

Published: Sept. 18, 2025, midnight
SPP1 as a key modulator of M2 macrophage polarization promotes endometriosis progression via activation of the FAK/PI3K/AKT pathway: A bioinformatics and experimental study.

Endometriosis (EMs) is a gynecological disorder characterized by chronic inflammation and an aberrant immune microenvironment. In this study, we integrated the GSE6364 dataset from the GEO database to identify differentially …

Published: Sept. 17, 2025, midnight
The strategic role of lipidomics in biomarker identification and diagnosis of gynecological diseases.

Lipidomics, an emerging field in medical research, has deepened our understanding of lipid metabolism, signal transduction pathways, and intercellular communication through qualitative and quantitative analyses of patient lipid profiles. It …

Published: Sept. 17, 2025, midnight
HeraNorm: an R shiny application for identifying optimal endogenous controls for miRNA and RNA assays in qPCR and ddPCR.

Normalization is a critical step in quantitative PCR (qPCR) and droplet digital PCR (ddPCR) experiments to ensure accurate and reproducible gene expression analysis. However, commonly used endogenous controls such as …

Published: Sept. 17, 2025, midnight
Noninvasive Detection and Thermal Ablation Therapy of Endometriosis Using Silica-Coated Gold Nanorods.

Endometriosis (EM) is a gynecological disease where endometrial tissue grows outside the uterus. Current diagnostic methods are mainly through surgical visualization with histological verification; there's a need for noninvasive approaches. …

Published: Sept. 17, 2025, midnight
Leveraging the role of the microbiome in endometriosis: novel non-invasive and therapeutic approaches.

Endometriosis (EMS) is an oestrogen-dependent condition characterised by ectopic endometrial-like tissue growth with a chronic and inflammatory nature leading to severe symptoms and reduced quality of life. Emerging evidence implicates …

Published: Sept. 16, 2025, midnight
Endometriosis and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis.

Background/Objectives: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and endometriosis are debilitating conditions that share overlapping features of chronic inflammation and immune dysregulation, yet their epidemiological relationship remains poorly characterized. The objective …

Published: Sept. 15, 2025, midnight
The effects of music listening intervention on postoperative care in unilateral vs. bilateral endometriotic cysts.

Endometriosis is a chronic gynecological condition that can result in pelvic pain and infertility, thereby significantly impacting women's reproductive health. Psychological disorders such as anxiety and depression are common in …

Published: Sept. 15, 2025, midnight
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