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M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy With Comorbid Traits.

Endometriosis is a common gynecologic condition that causes chronic, life-altering symptoms including pain and infertility. There is an urgent need for new non-hormonal targeted therapeutics to treat endometriosis, but until …

Published: Sept. 12, 2025, midnight
Understanding Endometriosis: A Broad Review of Its Causes, Management, and Impact.

Endometriosis is a complex gynecological condition affecting 10% of women globally, characterized by the growth of endometrial-like tissue outside the uterus, leading to chronic pelvic pain, infertility, reduced quality of …

Published: Sept. 12, 2025, midnight
Efficacy of Elagolix and Relugolix for the Treatment of Pelvic Pain in Patients With Endometriosis: A Systematic Review.

Endometriosis is a chronic gynecological condition commonly associated with pelvic pain, dysmenorrhea, dyspareunia, and infertility. Owing to the limitations and adverse effects of traditional hormonal therapies, this study aimed to …

Published: Sept. 12, 2025, midnight
Inguinal endometriosis: a rare entity of a common condition .

A woman in her mid-40s experienced a painful lump in the right groin area for 5 years, with exacerbation during menstruation, coughing and sneezing. Initial treatment with depot methylprednisolone acetate …

Published: Sept. 11, 2025, midnight
The Role of Endometriosis in Intestinal Inflammation: A Combined Mendelian Randomization and Cellular Study.

This study aims to assess whether endometriosis causally increases the risk of IBD through Mendelian randomisation (MR) analysis and to elucidate potential mechanisms using in vitro experiments. A two-sample Mendelian …

Published: Sept. 10, 2025, midnight
Vaginal endometriosis following uterine transplantation in a patient with Mayer-Rokitansky-Küster-Hauser syndrome: A unique case report.

Published: Sept. 10, 2025, midnight
Sigmoid colon endometriosis as an uncommon cause of large bowel obstruction: A case report.

Large bowel obstruction (LBO) is most commonly caused by neoplasms, but rare etiologies like endometriosis should be considered, as bowel involvement can mimic other gastrointestinal disorders and lead to obstruction. …

Published: Sept. 10, 2025, midnight
Evaluation and surgical approaches to gynecologic pelvic pain in pediatric patients.

Pelvic pain is a common concern among adolescent females, with gynecologic etiologies ranging from dysmenorrhea, most often due to endometriosis, to obstructive anomalies and adnexal masses. Evaluation requires a detailed …

Published: Sept. 10, 2025, midnight
Erastin-induced multi-pathway cell death in endometriosis: a mechanistic and translational narrative review.

This narrative review examines the therapeutic potential of Erastin and its derivatives for endometriosis (EMS) by integrating mechanistic, preclinical, and translational perspectives. We conducted a focused review of literature from …

Published: Sept. 10, 2025, midnight
Misdiagnosis in patients with obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome: a retrospective study of 164 cases.

The aim of this study was to summarize and analyze the incidence, underlying causes and related risk factors of misdiagnosis in patients with Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA) …

Published: Sept. 8, 2025, midnight
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