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C57BL/6J mice best recapitulate fibrosis and inflammatory pathophysiology in syngeneic mouse model of endometriosis.

Endometriosis (ENDO), a chronic inflammatory disease affecting approximately 190 million women globally, is characterized by fibrosis, a feature often challenging to replicate in murine models. To identify an optimal syngeneic …

Published: Aug. 8, 2025, midnight
Effects of Mono- (2-ethylhexyl) phthalate and Phthalic Acid Monobenzyl Ester on endometriosis using network toxicology, machine learning and molecular docking techniques.

Phthalate metabolites Mono- (2-ethylhexyl) phthalate(MEHP) and Phthalic Acid Monobenzyl Ester (MBZP) are widely present in the environment, can interfere with the endocrine system and accumulate in human tissues, and are …

Published: Aug. 8, 2025, midnight
In Vivo Shadows and In Vitro Light: The Early Embryological Journey Amid Endometriosis.

Endometriosis significantly impacts fertility through complex mechanisms. These include chronic inflammation, oxidative stress, and anatomical distortion. These mechanisms impair oocyte quality, embryo development, and implantation. While in vivo challenges persist, …

Published: July 29, 2025, midnight
Divergent Immune-Metabolic Profiles in Endometriosis and Ovarian Cancer: A Cross-Sectional Analysis.

Endometriosis and high-grade serous ovarian cancer (HGS-OC) share common features within the peritoneal immune microenvironment, yet they exhibit divergent clinical outcomes. This study aimed to dissect the immune-metabolic landscape of …

Published: July 12, 2025, midnight
Exploring the Immune System's Role in Endometriosis: Insights Into Pathogenesis, Pain, and Treatment.

Endometriosis is a common gynecological condition that usually affects women during their reproductive years. The main goal of this narrative review is to understand the role of the innate and …

Published: July 1, 2025, midnight
The role of m6A methylation in female reproductive physiology and pathology.

N6-methyladenosine (m6A) is a critical regulator of female reproductive physiology, yet existing reviews have focused predominantly on oocytes. The objective of this review is to systematically evaluate the regulatory effects …

Published: July 1, 2025, midnight
The Immune Microenvironment in Endometrial Carcinoma: Mechanisms and - Frontiers

The Immune Microenvironment in Endometrial Carcinoma: Mechanisms and Frontiers

Published: June 27, 2025, 10:51 p.m.
LIN28B Promotes the Progression of Endometrial Cancer through Upregulating MYC and Correlates with Immune Microenvironment - Frontiers

LIN28B Promotes the Progression of Endometrial Cancer through Upregulating MYC and Correlates with Immune Microenvironment Frontiers

Published: June 26, 2025, 1:55 p.m.
Infertility crisis: Experts warn of environmental toxins, lifestyle risks - Vanguard News

Infertility crisis: Experts warn of environmental toxins, lifestyle risks Vanguard News

Published: June 25, 2025, 11:48 p.m.
PCOS Endometrium Exhibits Altered Immune Environment, Impaired Hormone Signaling - Physician's Weekly

PCOS Endometrium Exhibits Altered Immune Environment, Impaired Hormone Signaling Physician's Weekly

Published: June 19, 2025, 9:44 p.m.
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