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Endometriosis-Associated Implantation Failure: Pathophysiology, Biomarkers, and Emerging Therapeutic Strategies.

Implantation failure remains a major challenge in assisted reproductive technology (ART) and is a significant contributor to infertility in women with endometriosis. Beyond mechanical distortion and ovarian dysfunction, increasing evidence …

Published: July 24, 2026, midnight
The Therapeutic Role of Dienogest in Endometriosis-Associated Pain: From Basics to Clinics.

The most common symptom of endometriosis is pain. The pathogenesis of endometriosis-associated pain remains unclear. In this review, we illustrate the pathogenesis of endometriosis-associated pain and the mechanisms of dienogest …

Published: July 23, 2026, midnight
The Molecular and Cellular Mechanisms of Melatonin: From Physiological Actions to Clinical Applications in Reproductive Medicine.

Melatonin has evolved from its classical role as a pineal-derived circadian regulator to a molecule increasingly recognized for its mitochondrial and cytoprotective functions. This review examines the molecular mechanisms and …

Published: July 22, 2026, midnight
Endometriosis: surgical management for fertility enhancement.

Endometriosis is a common, chronic inflammatory condition characterized by the presence of endometrium-like tissue outside of the uterus that can impact fertility through multiple mechanisms. In this review, the diagnosis, …

Published: July 22, 2026, midnight
Integrative Transcriptomic Analysis Identifies a Key Candidate Gene Bridging Inflammation and DNA Repair in Endometriosis.

Endometriosis is a chronic, estrogen-dependent inflammatory disorder characterized by the ectopic implantation of endometrial-like tissue. Although retrograde menstruation is highly prevalent, only a subset of women develops the disease. This …

Published: July 21, 2026, midnight
Robotic versus laparoscopic colectomy for deep infiltrative endometriosis of the bowel: a propensity-matched analysis of US-based hospitals.

Deep infiltrative endometriosis involving the bowel is a complex disease in which the optimal minimally invasive surgical approach remains uncertain, particularly regarding long-term fertility, recurrence, and healthcare utilization. We conducted …

Published: July 20, 2026, midnight
Salmonella-induced adnexal abscess superimposed on ovarian endometrioma and adenomyosis.

Salmonella-induced tubo-ovarian abscesses (TOAs) in patients with ovarian endometriomas and coexisting adenomyosis are rare and surgically challenging due to dense adhesions. We report a woman in her late 30s presenting …

Published: July 20, 2026, midnight
Associations between granulysin and ovarian endometriosis: A 2-sample Mendelian randomization study.

Endometriosis (EMS) is a chronic inflammatory disease defined by the presence of endometrial-like tissue outside the uterine cavity. Ovarian EMS is considered the most prevalent disease phenotype. However, the causal …

Published: July 19, 2026, midnight
When two diseases collide: Endometriosis as a risk factor for severe pelvic inflammatory disease.

Our objective was to compare the severity of pelvic inflammatory disease (PID) in hospitalized women with and without endometriosis, and to assess whether deep endometriosis is associated with worse clinical …

Published: July 19, 2026, midnight
Endometriosis Unveiled: A Tale of Two Extremes, From Acute Sepsis to Silent Suspicion.

Endometriosis may rarely present with atypical manifestations that closely mimic intra-abdominal malignancy or severe pelvic sepsis, resulting in significant diagnostic uncertainty. We present two contrasting cases of presumed severe endometriosis …

Published: July 18, 2026, midnight
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