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Selective Appendectomy in Patients Undergoing Minimally Invasive Surgery for Endometriosis: A Retrospective Cohort Study.

Background/Objectives: Endometriosis is a chronic inflammatory systemic disease that commonly affects bowel structures, including the appendix, where it may mimic or coexist with chronic appendicitis. Visual inspection alone often fails …

Published: Oct. 15, 2025, midnight
Impact of Minimally Invasive Surgery on Quality of Life and Infertility in Deep Infiltrating Endometriosis.

Background: Endometriosis is a chronic, estrogen-dependent inflammatory disease affecting up to 10% of women of reproductive age. It substantially impacts quality of life (QoL) through pelvic pain, infertility, and psychological …

Published: Oct. 14, 2025, midnight
The Role of the Microbiome in Endometriosis.

Endometriosis is a chronic gynecological disease characterized by the presence of endometrial-like tissue outside the uterus, leading to pain and infertility. Recent research has highlighted the important role of the …

Published: Oct. 13, 2025, midnight
Potential biomarkers for early detection of endometriosis: current state of art (what we know so far).

Endometriosis is a chronic gynecological condition characterized by the presence of endometrial-like tissue outside the uterine cavity. Its diagnosis remains a significant clinical challenge, often delayed by 7 to 12 …

Published: Oct. 13, 2025, midnight
Two Cases of Mesonephric-Like Adenocarcinoma Arising From Ovary and Peritoneal and Literature Review.

Reports of Mesonephric-like adenocarcinoma (MLA) arising from other than the ovary and uterus are exceedingly rare. This report details two cases of MLA in patients with a history of endometriosis. …

Published: Oct. 12, 2025, midnight
Efficacy of Organic Selenium Supplementation on Endometrioma Regression and Pain in Women With Endometriosis: A Triple-Blind Randomized Controlled Clinical Trial.

Endometriosis is a non-malignant, estrogen-dependent chronic inflammatory disorder that affects 10-15% of women during their reproductive years. Emerging evidence highlights the undeniable role of oxidative stress in the etiopathogenesis of …

Published: Oct. 10, 2025, midnight
NLRP3 Inflammasome in Gynecologic Inflammatory Diseases: Mechanisms, Pathophysiology, and Therapeutic Strategies.

The NOD-like receptor family containing pyridine domain 3 (NLRP3) inflammasome serves as a pivotal mediator of innate immune responses and a central driver of inflammatory processes. Upon detection of pathogenic …

Published: Oct. 10, 2025, midnight
Case Report: A patient with lynch syndrome with vaginal endometriosis-associated malignancy and synchronous colonic tubulovillous adenoma.

Endometriosis is a common gynecological condition. However, endometriosis-associated malignancies occur in up to 1% of women with endometriosis. Most cases of endometriosis-associated malignancy occur in the ovary, whereas 20% of …

Published: Oct. 8, 2025, midnight
Novel applications of gene and cell therapies in the treatment of gynecological disorders.

Gynecologic disorders, such as cervical and ovarian tumors, uterine fibroids, and endometriosis, present significant clinical challenges due to frequent recurrence, emerging chemoresistance, and undesirable effects associated with prolonged hormonal treatments. …

Published: Oct. 8, 2025, midnight
Endometriosis: Emerging barriers to care in sub-Saharan Africa.

Endometriosis is a leading cause of chronic pelvic pain and infertility, affecting an estimated 176 million women globally¹. In sub-Saharan Africa, its diagnosis and management remain constrained by persistent misconceptions …

Published: Oct. 7, 2025, midnight
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