A recent study has shown that myofibroblasts are primed for apoptosis when survival pathways are inhibited under fibrosis. This knowledge of apoptosis priming led to the development of methods to …
Ovarian endometriotic cysts are associated with an increased risk of clear cell and endometrioid carcinomas, as well as borderline neoplasms. Although contrast-enhancing nodules on magnetic resonance imaging (MRI) suggest malignancy, …
Endometriosis is a debilitating condition characterized by the growth of endometrial-like tissue outside the uterus, leading to chronic pain and inflammation. While its etiology remains complex, emerging evidence implicates environmental …
BACKGROUND Splenosis is the ectopic autotrasplantation of splenic tissue that can follow trauma to the spleen or splenectomy and can occur anywhere in the peritoneal cavity or extraperitoneally. Splenosis can …
Epithelial ovarian cancer commonly presents with vague symptoms that delay diagnosis until disease is advanced. Granulomatous peritonitis is a term used to describe granulomatous inflammation within the peritoneal cavity and …
In women with endometriosis, monocyte chemoattractant protein 1 (MCP-1) or chemokine (C-C motif) ligand 2 (CCL2) is elevated in serum, peritoneal fluid, and endometriotic lesions, though its exact role in …
Matrix metalloproteinases (MMPs) cleave proteins of extracellular matrix thus facilitating cellular invasion and cancer progression. High MMP-2 activity is frequently reported in several diseases including endometriosis and cancer. Endometriosis, though …
Ovarian squamous cell carcinoma [SCC] is a rare and aggressive malignancy that can mimic benign gynecological disorders, often leading to diagnostic delays and suboptimal management. Ureteral obstruction and subsequent hydroureteronephrosis …
Endometriosis may become malignant, and its diagnosis is challenging, especially in rare extra-ovarian sites like the rectum. Here, we describe the case of a 42-year-old woman who presented with intermittent …