Latest Articles

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Microbial harmony in female reproductive health: exploring the impact of intestinal flora on ovarian function and disease pathogenesis.

The intestinal microbiota is vast in type and quantity and it plays a critical role in regulating various physiological functions in the host, including intestinal function, immune response and energy …

Published: Nov. 15, 2024, midnight
Childhood adversity and risk of endometriosis, fibroids, and polycystic ovary syndrome: A systematic review.

While childhood adversity has been extensively studied in relation to various health outcomes, investigation of its association with gynecological conditions remains limited.

Published: Nov. 7, 2024, midnight
Crosstalk Between Oxidative Stress and Epigenetics: Unveiling New Biomarkers in Human Infertility.

The correlation between epigenetic alterations and the pathophysiology of human infertility is progressively being elucidated with the discovery of an increasing number of target genes that exhibit altered expression patterns …

Published: Nov. 7, 2024, midnight
Familial coaggregation and shared genetic influence between major depressive disorder and gynecological diseases.

The mechanism underlying the co-occurrence of major depressive disorder (MDD) and gynecological diseases remains unclear. This study aimed to investigate the familial co-aggregation and shared genetic loading between MDD and …

Published: Nov. 4, 2024, midnight
Investigating the metabolomic pathways in female reproductive endocrine disorders: a Mendelian randomization study.

Reproductive endocrine disorders (RED), including polycystic ovary syndrome (PCOS), endometriosis (EMs), and female infertility (FI), significantly affect women's health globally, with varying prevalence across different regions. These conditions can be …

Published: Oct. 31, 2024, midnight
Advances in Mesenchymal Stem Cell Research Applications for Female Infertility-Mechanisms, Efficacy Parameters, Challenges and Future Roadmap.

Infertility affects approximately 15-20% of couples globally, with female factors contributing to nearly half of cases. Conditions such as polycystic ovary syndrome, endometriosis, tubal damage and premature ovarian failure are …

Published: Oct. 8, 2024, midnight
Impact of GnRH antagonist pretreatment on oocyte yield after ovarian stimulation: A retrospective analysis.

The study investigates whether a 3-day pretreatment course with a GnRH antagonist in the early follicular phase has an impact on the number of retrieved COCs in a GnRH antagonist …

Published: Oct. 7, 2024, midnight
Carnitine traffic and human fertility.

Carnitine is a vital molecule in human metabolism, prominently involved in fatty acid β-oxidation within mitochondria. Predominantly sourced from dietary intake, carnitine also derives from endogenous synthesis. This review delves …

Published: Oct. 3, 2024, midnight
The role of RAD51 regulators and variants in primary ovarian insufficiency, endometriosis, and polycystic ovary syndrome.

The study of RAD51 regulators in female reproductive diseases has novel biomarker potential and implications for therapeutic advancement. Regulators of RAD51 play important roles in maintaining genome integrity and variations …

Published: Sept. 28, 2024, midnight
An illustrated review on herbal medicine used for the treatment of female infertility.

Infertility is one of the significant global issues that affects approximately 15-17 % of couples worldwide, with around 50 % of cases being attributed to female infertility factors. The exploration …

Published: Sept. 27, 2024, midnight
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