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Establishment and Characterization of a New Immortalized Human Adenomyosis Epithelial-Like Cell Line, tAEC21†.

Adenomyosis occurs when endometrial glands and stroma grow within the uterine myometrium. As a clinically significant disease, adenomyosis causes substantial pelvic pain and heavy menstrual bleeding. It remains understudied due …

Published: Nov. 20, 2025, midnight
Endometriosis - on the intersection of modern environmental pollutants and ancient genetic regulatory variants.

Endometriosis is a chronic, estrogen-driven inflammatory disorder affecting approximately 10% of reproductive-aged women globally. Despite increasing genomic insights into advanced-stage disease, the genetic underpinnings of early-stage endometriosis remain poorly understood, …

Published: Nov. 20, 2025, midnight
Lack of Scientific Evidence for the Use of Gestrinone in the Treatment of Lipedema: A Systematic Review.

Lipedema is a chronic, progressive disorder marked by the abnormal accumulation of subcutaneous adipose tissue, predominantly in the lower body and almost exclusively affecting women. In recent years, the off-label …

Published: Nov. 19, 2025, midnight
Curcumol alleviates endometriosis via correcting the aberrant activation of Fas/RIPK1-mediated PANoptosis.

Endometriosis (EMs) is an estrogen-dependent chronic inflammatory disease. While apoptosis resistance (evidenced by Bcl-2 upregulation and Bax/caspase-3 downregulation) remains a hallmark of EMs, recent studies reveal a paradoxical coexistence of …

Published: Nov. 18, 2025, midnight
Ingenus Pharmaceuticals Announces FDA Approval and Launch of First and Only Generic Equivalent to Premarin® Tablets (Conjugated Estrogens Tablets, USP) - BioSpace

Ingenus Pharmaceuticals Announces FDA Approval and Launch of First and Only Generic Equivalent to Premarin® Tablets (Conjugated Estrogens Tablets, USP) BioSpace

Published: Nov. 14, 2025, 11:59 a.m.
Ingenus Pharmaceuticals Announces FDA Approval and Launch of First and Only Generic Equivalent to Premarin® Tablets (Conjugated Estrogens Tablets, USP) - Morningstar

Ingenus Pharmaceuticals Announces FDA Approval and Launch of First and Only Generic Equivalent to Premarin® Tablets (Conjugated Estrogens Tablets, USP) Morningstar

Published: Nov. 13, 2025, 3:15 p.m.
Interventions for endometriosis-related pain and infertility: a protocol for systematic review and network meta-analysis.

Endometriosis, a chronic oestrogen-dependent disorder, presents significant clinical challenges including pelvic pain, dysmenorrhoea, dyspareunia and infertility. While numerous interventions exist, evidence guiding the choice among surgical, hormonal and non-hormonal therapies …

Published: Nov. 13, 2025, midnight
Mechanistic Insights into the Anti-Inflammatory and Anti-Proliferative Effects of Selected Medicinal Plants in Endometriosis.

Endometriosis involves oestrogen-dependent chronic inflammation and the abnormal proliferation of ectopic endometrial tissue. Conventional hormonal therapies suppress systemic oestrogen, but do not fully address local oxidative and inflammatory signalling. This …

Published: Nov. 12, 2025, midnight
A Case of Appendiceal Endometriosis Diagnosed as Acute Appendicitis and Treated With Laparoscopic Appendectomy.

Appendiceal endometriosis is an uncommon manifestation of extrapelvic endometriosis that can clinically and radiologically mimic acute appendicitis. We report the case of a 41-year-old woman who presented with acute right …

Published: Nov. 9, 2025, midnight
Diagnostic Challenge of Appendiceal Endometriosis: A Case Report.

Endometriosis is a chronic, estrogen-dependent disease affecting women of reproductive age. Although extragenital involvement is not uncommon, appendiceal endometriosis is a rare entity that may present with acute abdominal pain, …

Published: Nov. 8, 2025, midnight
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