This study investigates the association between diagnostic delay (DD) and clinical and behavioral variables among Japanese women with endometriosis, and explores an optimal cut-off point distinguishing short and long DD.
Steroid receptor coactivators (SRCs) are master regulators of nuclear receptor signaling and play essential roles in female reproductive physiology. By integrating steroid hormone signaling with growth factors and metabolic pathways, …
Although observational studies suggest a link between socioeconomic status (SES) and hormone-related gynecologic diseases, the causal direction and mediating mechanisms remain unclear. This study aims to explore the causal relationships …
Background: Background: Endometriosis affects 10% of women of reproductive age. Despite the well-known association between endometriosis and infertility, the mechanisms underlying this association remain to be elucidated. Methods: Implantation and …
Objective: To comprehensively examine the qualitative results of current studies reporting the efficacy of digital health (DH) technologies in the treatment of chronic pelvic pain syndromes (CPPS) and to describe …
Endometriosis (EMs) and recurrent miscarriage (RM) represent major reproductive health challenges. This study investigates the involvement of endothelial-mesenchymal transition (EndMT) in these conditions through integrative bioinformatics analysis, focusing on the …
Diet may play a crucial role in managing endometriosis. Dietary interventions could help women with endometriosis improve their quality of life and reduce pain symptoms. The aim of this study …
Endometriosis (EMT) is a prevalent gynecological disorder characterized by chronic pain, menstrual irregularities, and infertility. This study aims to evaluate the global burden of EMT from 1990 to 2021 and …
This pilot study evaluated Synuclein gamma (SNCG) and B-Cell Lymphoma 6 (BCL6) proteins as potential non-invasive biomarkers in serum and menstrual fluid (MF) to differentiate endometriosis patients from non-endometriosis and …
Chronic pain is a widespread condition affecting millions globally, placing significant strain on healthcare systems, as evidenced by the current opioid crisis. Despite advances in pain management, conventional treatments often …