Latest Articles

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Transfer of the Oral Gonadotropin-Releasing Hormone Receptor Antagonist Relugolix Into Breast Milk of Healthy Lactating Women.

Relugolix is an oral gonadotropin-releasing hormone receptor antagonist that suppresses sex steroid hormones and is approved as monotherapy for prostate cancer and as a fixed-dose combination with estradiol/norethindrone for the …

Published: Feb. 1, 2025, midnight
Investigating racial disparities in drug prescriptions for patients with endometriosis.

We assess racial disparities in medication prescription patterns for endometriosis patients across Medicaid administrative claims data. We use ATC 3rd level drug codes to identify drug classes prescribed significantly more …

Published: Jan. 30, 2025, midnight
Weighing up GnRH agonist therapy for endometriosis: outcomes and the treatment paradigm.

Endometriosis is a chronic inflammatory estrogen-dependent disease affecting 10% of women worldwide leading to chronic pelvic pain and infertility which may be treated clinically or surgically.

Published: Jan. 25, 2025, midnight
Clinical effectiveness of progestogens compared to combined oral contraceptive pills in the treatment of endometriosis: A systematic review and meta-analysis.

Endometriosis involves the growth of endometrium-like cells outside the uterus, affecting reproductive-aged women. Symptoms such as dysmenorrhea, pelvic pain, and infertility significantly impair quality of life. Among therapeutic options, progestogens …

Published: Jan. 23, 2025, midnight
Female chronic pelvic pain: From trauma-informed assessment to evidence-based treatment.

Female chronic pelvic pain (CPP) is a common, complex, multifactorial disorder that can negatively affect sexual functioning and emotional well-being. Effective assessment necessitates a comprehensive patient history and trauma-informed physical …

Published: Jan. 22, 2025, midnight
Selective progesterone receptor modulators for the treatment of dysmenorrhea: an update.

Dysmenorrhea is a painful symptom associated with uterine contractions and menstrual bleeding and is treated by administering analgesic drugs. Since progesterone receptors (PRs) have a major role in regulating uterine …

Published: Jan. 14, 2025, midnight
Endometriosis and risk of depression among oral contraceptive users: a pooled analysis of cohort studies from 13 countries.

Does endometriosis affect the mental health of women using oral contraceptives?

Published: Jan. 12, 2025, midnight
Validation of Tumor Budding as a Prognostic Factor in Ovarian Clear Cell Carcinoma Using an Independent Cohort.

Ovarian clear cell carcinoma (OCCC) is an endometriosis-related neoplasm, in which traditional histologic grading does not show prognostic significance. Tumor budding was associated with poorer outcomes in OCCC in previous …

Published: Jan. 10, 2025, midnight
Optimization and Evaluation of Cannabis-Based Magistral Formulations: A Path to Personalized Therapy.

The official implementation of pharmaceutical-grade cannabis raw materials for medicinal use has permitted doctors to prescribe and pharmacists to prepare cannabis-based formulations. The objective of the pharmaceutical development and manufacturing …

Published: Jan. 9, 2025, midnight
A Multimodal Approach to Symptomatic Endometriosis: A Proposed Algorithm for Clinical Management.

Recent research has proven that peripheral (PS) and central sensitization (CS), mental health, and myofascial dysfunction all play a role, alongside nociception, in the genesis and in the perpetuation of …

Published: Jan. 7, 2025, midnight
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