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Endometrial Cancer: Dostarlimab/Chemo Improves OS in Frontline RUBY Trial - Targeted Oncology

Endometrial Cancer: Dostarlimab/Chemo Improves OS in Frontline RUBY Trial Targeted Oncology

Published: Oct. 22, 2025, 5:11 p.m.
Dana-Farber Research Uncovers Potential Targeted Therapy for Endometrial Cancer - Dana-Farber Cancer Institute

Dana-Farber Research Uncovers Potential Targeted Therapy for Endometrial Cancer Dana-Farber Cancer Institute

Published: Oct. 21, 2025, 9 a.m.
Integrative transcriptomic analysis identifies shared EndMT-related gene signatures in endometriosis and recurrent miscarriage.

Endometriosis (EMs) and recurrent miscarriage (RM) represent major reproductive health challenges. This study investigates the involvement of endothelial-mesenchymal transition (EndMT) in these conditions through integrative bioinformatics analysis, focusing on the …

Published: Oct. 21, 2025, midnight
IL-6 Inhibits Invasion in a Murine Model of Endometriosis.

Endometriosis is a gynecological inflammatory disorder characterized by the presence of endometrial tissue outside of the uterus. It affects 10-15% of reproductive aged women, causing pelvic pain and infertility. Existing …

Published: Oct. 21, 2025, midnight
'En bloc' peritoneal mesometrial resection (PMMR) and pelvic targeted compartmental lymphadenectomy (TCL) for management of patients with endometrial cancer - feasibility and safety study of a 'new kid on the block' in robotic surgery.

Robotic Peritoneal Mesometrial Resection and Targeted Compartmental Lymphadenectomy (PMMR + TCL) is a procedure following Cancer Field Surgery concept for endometrial cancer (EC), enabling superior locoregional control without adjuvant irradiation. …

Published: Oct. 21, 2025, midnight
Pro-endometriosis macrophage release of IL-33 is key for endometriosis pain and lesion formation.

Endometriosis is a painful gynecological inflammatory disease affecting up to 10% of females. When released by sensory neurons, calcitonin gene-related peptide (CGRP) shapes immunity, a process known as neuroimmune communication. …

Published: Oct. 21, 2025, midnight
Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas - Nature

Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas Nature

Published: Oct. 20, 2025, 9:19 a.m.
Cyclana Bio Raises £5M to Reverse Endometriosis Through Extracellular Matrix Targeting - Femtech Insider

Cyclana Bio Raises £5M to Reverse Endometriosis Through Extracellular Matrix Targeting Femtech Insider

Published: Oct. 20, 2025, 8:02 a.m.
Shaoyao Gancao Decoction: a comprehensive review of modern clinical applications and underlying pharmacological mechanisms.

Shaoyao Gancao Decoction, a classic formula from Zhang Zhongjing in the Han Dynasty, has the effects of regulating the function of the liver, relieving spasm and stopping pain. Traditionally, it …

Published: Oct. 20, 2025, midnight
Addressing Meta-Inflammation in the Comprehensive Management of Chronic Pain.

Chronic pain is a widespread condition affecting millions globally, placing significant strain on healthcare systems, as evidenced by the current opioid crisis. Despite advances in pain management, conventional treatments often …

Published: Oct. 18, 2025, midnight
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