Single-Cell Transcriptomics Reveals Biomarkers for NK Cell Dysfunction in Endometriosis-Associated Immune Dysregulation.
Endometriosis (EM) is associated with immune dysregulation, while dysfunction of natural killer (NK) cells is regarded as a key mechanism underlying immune escape and the persistent growth of ectopic lesions.
YWHAZ Loss Is Associated With Endometrial Dysfunction in Proliferative Phase Endometriosis.
Endometriosis is an estrogen-dependent inflammatory disorder frequently associated with infertility and characterized by progesterone resistance and impaired endometrial receptivity. While ectopic lesions define the disease, accumulating evidence indicates that molecular …
Endometriosis-Associated Neoplasms: A Review of Clinicopathologic Features and Common Diagnostic Challenges.
Neoplastic potential of endometriosis is well established, albeit rare, and endometriosis-associated neoplasms are frequently encountered in clinical practice.
Endometriosis is increasingly recognized as a systemic disorder involving complex interactions between nerves and immune cells, driving chronic pain and inflammation beyond the initial theories. Recent breakthroughs highlight aberrant sensory …
Regarding "Is endometriosis staging related to the type and intensity of patients' complaints? A systematic review and meta-analysis": Toward a symptom-oriented framework in endometriosis.
Genetics of Endometriosis-Associated Ovarian Cancer: A Systematic Review.
Up to 1.6% of patients with endometriosis develop epithelial ovarian carcinoma. The genetic overlap between endometriosis and ovarian cancer has not been fully characterized. This review aims to describe the …
Comparing psychological distress, health-related quality of life and pain in individuals diagnosed with endometriosis and suspected to have endometriosis: A cross-sectional analysis.
To assess whether pain, psychological distress, and health-related quality of life (HRQoL) differ in individuals diagnosed with endometriosis and those suspected to have endometriosis.
A meta-umbrella review of risk factors for vulvodynia: evidence from demographic, psychosocial, and biomedical domains.
Vulvodynia is a chronic vulvar pain condition significantly affecting the quality of life. Its multifactorial etiology is not fully understood, and comprehensive pooled data on associated risk factors are lacking …