Expanding the spectrum of AFF2 undifferentiated sarcoma associated to endometriosis: a novel ZDHHC9::AFF2 fusion sarcoma with high-grade features and poor prognosis.
The AFF2 gene encodes a protein involved in transcriptional regulation and chromatin remodeling. While primarily associated with Fragile X syndrome, AFF2 fusions have recently been identified in certain malignancies, mostly …
[Main aspects of epigenetics of gestational and female genital tumors].
The genotype of our cells is almost the same for all cells in our body, but due to epigenetic effects, their phenotype can show significant differences. Epigenetics is a relatively …
Appendiceal endosalpingiosis: a rare case with potential implications for gynecological malignancy.
Appendiceal endosalpingiosis is an exceedingly rare histopathologic finding with uncertain clinical significance and unknown implications for management. Most often, endosalpingiosis occurs within ovary, fallopian tube, omentum, and uterus. Previous literature …