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GRB2 regulation of essential signaling pathways in the endometrium is critical for implantation and decidualization.

Over 75% of failed pregnancies involve implantation defects. Growth factor receptor-bound protein 2 (GRB2) is an adaptor protein involved in signal transduction and cell communication. Here we show that the …

Published: March 4, 2025, midnight
MCP-1 promotes ILK phosphorylation at Ser246 during endometriosis development and affects the pregnancy outcome.

In women with endometriosis, monocyte chemoattractant protein 1 (MCP-1) or chemokine (C-C motif) ligand 2 (CCL2) is elevated in serum, peritoneal fluid, and endometriotic lesions, though its exact role in …

Published: March 4, 2025, midnight
Tele-patient-reported outcome measures (telePROM) in follow-up of endometriosis: a validity and test-retest reliability study of an endometriosis-specific questionnaire (EQ).

Patient-Reported Outcome (PRO) measures supported by a severity algorithm may serve as a decision aid for triage and consultation in follow-up of patients with endometriosis. In a new follow-up regime, …

Published: March 3, 2025, midnight
Surgical exploration of primary umbilical and inguinal canal endometriosis: a cutaneous conundrum.

Primary cutaneous endometriosis and inguinal endometriosis (IEM) are rare, representing less than 1% and under 0.6% of extragenital and extrapelvic endometriosis, respectively. Co-occurrence in the same patient is exceedingly rare, …

Published: March 3, 2025, midnight
FOXA2 loss results in an increase of endometriosis development and LIF reveals a therapeutic effect for endometriosis.

Endometriosis, characterized by the growth of uterine-like tissue outside the uterus, causes chronic pain and infertility. Current diagnostic and therapeutic strategies have notable limitations, including delayed diagnosis and adverse effects. …

Published: March 2, 2025, 12:04 a.m.
Spontaneous hemoperitoneum in the second trimester of pregnancy with a favorable outcome: a case report.

Spontaneous hemoperitoneum in pregnancy is extremely rare but may cause severe hemorrhage, resulting in a high rate of mortality. We report a case of a primigravid woman who complained of …

Published: March 1, 2025, 12:15 a.m.
Unilateral ureteral endometriosis masquerading as a ureteral tumor and resulting in complete loss of renal function: A case report.

Ureteral endometriosis is a rare manifestation of endometriosis that involves the infiltration of endometrial tissue into the ureters, leading to ureteral obstruction and potential renal dysfunction. However, its preoperative diagnosis …

Published: March 1, 2025, 12:10 a.m.
Stigma and discrimination experienced by Black women with endometriosis in the Washington, DC, Metropolitan area: A pilot of the ENDO-served study.

Medical racism perpetuates health inequities contributing to why Black people in the United States (US) experience worse health outcomes when compared to non-Hispanic White populations. In terms of endometriosis, research …

Published: March 1, 2025, midnight
Endo Belly: A Mixed Methods Exploration of Body Image, Disordered Eating, and Psychopathology in Endometriosis.

There is increasing interest in the impact of endometriosis on body image, however, there is minimal understanding of the presence and nature of disordered eating. As body image dissatisfaction is …

Published: March 1, 2025, midnight
Unveiling the connection: asthma and endometriosis - a comprehensive systematic review and meta-analysis.

Asthma and endometriosis are two prevalent chronic conditions that affect a significant portion of the population. Both conditions have been linked to inflammatory processes and immune dysregulation, suggesting the possibility …

Published: March 1, 2025, midnight
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