Endometriosis, subclinical cardiac remodeling, and cardiovascular risk: mechanistic insights from cardiac magnetic resonance and mediation analysis.
Endometriosis is a systemic gynecological disorder affecting ~ 10% of reproductive-aged women and shares pathophysiological features with cardiovascular disease (CVD). However, its associations with cardiac remodeling and CVD risk, as …
Estradiol alters actin and protrusion dynamics in endometriotic epithelial cells.
Estradiol (E2), a sex steroid hormone molecule, plays a key role in regulating the actin and shape dynamics of cells in a multitude of normal and pathophysiological conditions. While cytoskeletal …
Terazosin as a Non-Hormonal Treatment for Endometriosis.
Endometriosis is a chronic, estrogen-dependent inflammatory disease including aberrant local steroidogenesis, inflammation, angiogenesis, oxidative stress, and prostaglandin-mediated pain. Given the elevated adrenergic receptor expression in endometriotic lesions and the potential …
Expression of concern to "Evaluation of depression and sleep disorders in the preoperative and postoperative period in stage 4 endometriosis patients" [Eur. J. Obstet. Gynecol. Reprod. Biol. 264 (2021) 254-258].
Sex-specific risk factors for stroke in women: Focus on the 2024 AHA/ASA guideline.
Women are less likely to have a stroke compared with men, but certain sex-specific risk factors can increase their risk for ischemic or hemorrhagic stroke later in life. The 2024 …