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Non-inferiority study to compare the efficacy of relugolix with dienogest for endometriosis-associated pain and usefulness of administering relugolix prior to dienogest (READY study): study protocol for a multicenter randomized controlled study.

Endometriosis presents as endometrial tissue growths outside the uterine cavity with its major symptoms including dysmenorrhea and infertility. Progestin preparations, such as dienogest, are the first-line therapy for endometriosis symptoms, …

Published: Feb. 6, 2025, midnight
Unraveling the role of lncRNA in Endometriosis-Associated immune system Dysregulation: Exploring the intricate immunological changes and disrupted signaling pathways.

A chronic illness known as endometriosis impacts women who are of reproductive maturity. It may be a factor in fertility problems, breast or ovarian cancer, asthma, cardiovascular illness, or pelvic …

Published: Feb. 5, 2025, midnight
Bringing Endometriosis to the Road of Contemporary Pain Science.

Endometriosis pain is mainly understood based on peripheral lesion characteristics and an outdated perspective equating nociception with pain. This limited view may divert understanding of interventions beyond peripheral logic, leading …

Published: Feb. 5, 2025, midnight
Evaluation of serum and peritoneal fluid mannose-binding lectin associated serine protease-3, adipsin, properdin, and complement factor-H levels in endometriosis patients.

Endometriosis is a chronic disease which has been reported to be associated with distorted immune mechanisms. The alternative pathway is a complement system which plays a role in immune defense. …

Published: Feb. 5, 2025, midnight
Pain science education concepts for pelvic pain: an e-Delphi of expert clinicians.

Persistent pelvic pain is a prevalent condition that negatively impacts one's physical, psychological, social, and sexual wellbeing. Pain science education (PSE) involves learning about the biology of pain and is …

Published: Feb. 4, 2025, midnight
Informational support for women with endometriosis: a scoping review.

Ten per cent of women of reproductive age suffer from endometriosis, a painful and incurable disease that leaves women with severe implications for their health and overall well-being. Due to …

Published: Feb. 3, 2025, midnight
Comprehensive Management of Bowel Endometriosis: Surgical Techniques, Outcomes, and Best Practices.

Bowel endometriosis is a complex condition predominantly impacting women in their reproductive years, which may lead to chronic pain, gastrointestinal symptoms, and infertility. This review highlights current approaches to the …

Published: Feb. 3, 2025, midnight
Potential biomarkers and immune infiltration linking endometriosis with recurrent pregnancy loss based on bioinformatics and machine learning.

Endometriosis (EMs) is a chronic inflammatory disease characterized by the presence of endometrial tissue in the non-uterine cavity, resulting in dysmenorrhea, pelvic pain, and infertility. Epidemiologic data have suggested the …

Published: Feb. 3, 2025, midnight
Ileal Endometriosis: A Rare Case.

Endometriosis occurs when tissue similar to the lining of the uterus grows outside of it. Although it typically affects organs within the pelvis, it can sometimes spread to other areas …

Published: Feb. 3, 2025, midnight
The NLRP3 activation-related signature predicts the diagnosis and indicates immune characteristics in endometriosis.

Endometriosis (EMS) is a prevalent gynecological disease that leads to chronic pelvic pain and infertility in women of reproductive age. However, the underlying pathogenic genes and effective treatment for EMS …

Published: Jan. 31, 2025, midnight
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