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C57BL/6J mice best recapitulate fibrosis and inflammatory pathophysiology in syngeneic mouse model of endometriosis.

Endometriosis (ENDO), a chronic inflammatory disease affecting approximately 190 million women globally, is characterized by fibrosis, a feature often challenging to replicate in murine models. To identify an optimal syngeneic …

Published: Aug. 8, 2025, midnight
Effects of Mono- (2-ethylhexyl) phthalate and Phthalic Acid Monobenzyl Ester on endometriosis using network toxicology, machine learning and molecular docking techniques.

Phthalate metabolites Mono- (2-ethylhexyl) phthalate(MEHP) and Phthalic Acid Monobenzyl Ester (MBZP) are widely present in the environment, can interfere with the endocrine system and accumulate in human tissues, and are …

Published: Aug. 8, 2025, midnight
Artificial intelligence-driven decision tree model for predicting quality of life determinants in women with endometriosis.

Endometriosis significantly impacts the quality of life (QoL) of affected women due to its complex symptomatology. This study aimed to develop a decision tree-based model to identify the key determinants …

Published: Aug. 8, 2025, midnight
Barriers to gender affirming healthcare for transgender and non-binary people with endometriosis.

Endometriosis is a chronic and painful gynaecological condition that is known to negatively affect people's quality of life. Much of endometriosis research has focussed on cisgender women with endometriosis, but …

Published: Aug. 8, 2025, midnight
Cervical endometriosis mimicking cervical adenocarcinoma: A case report.

Cervical endometriosis is a rare benign condition characterized by ectopic endometrial glands and stroma within the cervix. Its clinical and imaging features resemble those of cervical adenocarcinoma, making preoperative diagnosis …

Published: Aug. 7, 2025, midnight
Unraveling the Core of Endometriosis: The Impact of Endocrine Disruptors.

Globally, endometriosis affects almost 10% of reproductive-aged women, leading to chronic pain and discomfort. Endocrine-disrupting compounds (EDCs) seem to play a pivotal role as a causal factor. The current manuscript …

Published: Aug. 6, 2025, midnight
Correlation of Sonographic and Intraoperative Findings of Deep-Infiltrating Endometriosis.

Endometriosis is a chronic inflammatory condition affecting approximately 5%-10% of reproductive-aged women. Transvaginal ultrasound (TVUS) is increasingly used to diagnose deep-infiltrating endometriosis (DIE). This study assesses the sonographic accuracy of …

Published: Aug. 6, 2025, midnight
Identification of Candidate Genes for Endometriosis in a Three-Generation Family with Multiple Affected Members Using Whole-Exome Sequencing.

Background: Endometriosis is a chronic inflammatory condition affecting 10-15% of women of reproductive age. Genome-wide association studies (GWASs) have accounted for only a fraction of its high heritability, indicating the …

Published: Aug. 6, 2025, midnight
Ultrasound Follow-Up in young women with severe dysmenorrhea predicts early onset of endometriosis.

To evaluate the progression of endometriosis and painful symptoms in young women (≤ 25 years) with severe dysmenorrhea (Visual Analogue Scale score ≥ 7), with or without ultrasound-detected endometriosis, over …

Published: Aug. 5, 2025, midnight
Design of a peripherally biased NPSR1 antagonist for neuropeptide S induced inflammation.

Neuropeptide S (NPS) is a potent agonist for the GPCR receptor NPSR1, implicated in various physiological and pathological processes, including inflammation. NPSR1 gene polymorphisms have been linked to asthma, inflammatory …

Published: Aug. 5, 2025, midnight
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