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Exosomes from the Uterine Cavity Mediate Immune Dysregulation via Inhibiting the JNK Signal Pathway in Endometriosis.

Endometriosis is a chronic inflammatory disease with an uncertain pathogenesis. Peritoneal immune dysregulation plays an important role in the pathogenesis of endometriosis. Exosomes are messengers of intercellular communication. This study …

Published: Dec. 2, 2022, midnight
Endometriosis Is Undervalued: A Call to Action.

Endometriosis is an inflammatory chronic pain condition caused by uterine tissue growing outside of the uterus that afflicts at least 11% of women (and people assigned female at birth) worldwide. …

Published: May 10, 2022, midnight
Insights Into the Regulation of Gynecological Inflammation-Mediated Malignancy by Metalloproteinases.

Gynecological illness accounts for around 4.5% of the global disease burden, which is higher than other key global health concerns such as malaria (1.04%), TB (1.9%), ischemic heart disease (2.2%), …

Published: Nov. 29, 2021, midnight
High Prediagnosis Inflammation-Related Risk Score Associated with Decreased Ovarian Cancer Survival.

There is suggestive evidence that inflammation is related to ovarian cancer survival. However, more research is needed to identify inflammation-related factors that are associated with ovarian cancer survival and to …

Published: Nov. 17, 2021, midnight
Placenta Previa Complicated with Endometriosis: Contemporary Clinical Management, Molecular Mechanisms, and Future Research Opportunities.

Endometriosis is a common gynecological disease characterized by chronic inflammation, with an estimated prevalence of approximately 5-15% in reproductive-aged women. This study aimed to assess the relationship between placenta previa …

Published: Oct. 26, 2021, midnight
Human Exposure to Polychlorinated Biphenyls (PCBs) and The Risk of Endometriosis: A Systematic Review and Meta-Analysis Protocol.

Endometriosis is one of the gynecological disorders and its prevalence is estimated to 8.10% of reproductive-age women. In Iran, the frequency of endometriosis was reported at 29% among infertile women. …

Published: Sept. 21, 2021, midnight
Navigating possible endometriosis in primary care: a qualitative study of GP perspectives.

Endometriosis affects approximately 6-10% of women, with well documented delays between initial presentation with symptoms and diagnosis. In England, women typically seek help first in primary care, making this setting …

Published: Aug. 26, 2021, midnight
A clearer view on ovarian clear cell carcinoma.

Ovarian clear cell carcinoma (OCCC) is a less common subtype accounting for approximately 5% of all epithelial ovarian cancers (EOCs). Clinical experience and research findings confirm the remarkable differences in …

Published: Aug. 17, 2021, midnight
The Immunohistochemical Expression of MCM-3, -5, and -7 Proteins in the Uterine Fibroids.

Uterine fibroids are the most common mesenchymal uterine neoplasms; their prevalence is estimated in 40%-60% of women under 35 and in 70%-80% of women over 50 years of age. The …

Published: July 25, 2021, midnight
Identification and Exploration of Novel Macrophage M2-Related Biomarkers and Potential Therapeutic Agents in Endometriosis.

Endometriosis (EM) is a chronic neuroinflammatory disorder that is associated with pain and infertility that affects ∼10% of reproductive-age women. The pathophysiology and etiology of EM remain poorly understood, and …

Published: July 6, 2021, midnight
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