Glycolytic reprogramming and MYH10 K1520 lactylation mediate eutopic endometrial collagen I deposition driven by PKM2-packaged ectopic endometrial extracellular vesicles.
Endometriosis (EMs) is characterized by ectopic lesions that disrupt endometrial decidualization, a process frequently accompanied by aberrant collagen deposition and closely linked to clinical infertility. Extracellular vesicles (EVs) are key …
Efficacy and Safety of Elagolix Versus Dienogest for Treatment of Moderate-to-Severe Endometriosis Pain: A Phase III, Multicentric, Double-Blind, Active-Controlled, Non-Inferiority Study.
To compare the efficacy, safety and tolerability of elagolix with dienogest in women with moderate-to-severe endometriosis-associated pain.
The Incidence of Negative Laparoscopy for Pelvic Pain Stratified by Level of Training and Location of Service Provision.
Systematic reduction of negative laparoscopy for pelvic pain is crucial to reducing surgical morbidity, improving diagnostic accuracy and minimising cost. This study aims to determine the incidence and consider the …
Risk of congenital anomalies among infants of patients with endometriosis: a population-based cohort study.
Maternal chronic conditions are implicated as risk factors for congenital anomalies, but few studies have assessed reproductive conditions such as endometriosis. Given the association between endometriosis and infertility requiring fertility …
Response to the Letter: Observations and points of interest regarding bioinformatics predictions of miRNA targeting syncytin genes in endometriosis and miscarriage.
[Catamenial Pneumothorax During Endometriosis Treatment].
Here, we report a case of catamenial pneumothorax that occurred during endometriosis treatment. A 46-year-old woman presented with a history of right pneumothorax. At 43 years of age, the patient …
Applied surgical anatomical approach to pudendal nerve: Step-by-step key neurovascular structures for pelvic nerve surgery.
To define and demonstrate a step-by-step surgical anatomical approach to pudendal nerve dissection using female cadavers, focusing on the identification of safe roadmap and key neurovascular structures to optimize pelvic …