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Development of a Novel Machine Learning Model for Automatic Assessment of Quality of Transvaginal Ultrasound Images From Multi-Annotator Labels.

Accurate diagnosis of pathology from ultrasound images is reliant upon images of a suitable diagnostic quality being acquired. This study aimed to create a novel machine learning model to automatically …

Published: Sept. 22, 2025, midnight
Potential Changes in the Eutopic Endometrium in Endometriosis: A Narrative Review.

Endometriosis is a disease characterized by the presence of ectopic endometrium, mainly within the peritoneal cavity, and is associated with the development of inflammation due to cyclic endometrial alterations. The …

Published: Sept. 22, 2025, midnight
Balancing Decidualization, Autophagy, and Cellular Senescence for Reproductive Success in Endometriosis Biology.

Endometriosis is a chronic disease characterized by the ectopic presence of endometrial cells that evade apoptosis and survive and proliferate under harsh environmental conditions. It is closely associated with infertility …

Published: Sept. 18, 2025, midnight
The strategic role of lipidomics in biomarker identification and diagnosis of gynecological diseases.

Lipidomics, an emerging field in medical research, has deepened our understanding of lipid metabolism, signal transduction pathways, and intercellular communication through qualitative and quantitative analyses of patient lipid profiles. It …

Published: Sept. 17, 2025, midnight
M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy With Comorbid Traits.

Endometriosis is a common gynecologic condition that causes chronic, life-altering symptoms including pain and infertility. There is an urgent need for new non-hormonal targeted therapeutics to treat endometriosis, but until …

Published: Sept. 12, 2025, midnight
Evaluation and surgical approaches to gynecologic pelvic pain in pediatric patients.

Pelvic pain is a common concern among adolescent females, with gynecologic etiologies ranging from dysmenorrhea, most often due to endometriosis, to obstructive anomalies and adnexal masses. Evaluation requires a detailed …

Published: Sept. 10, 2025, midnight
Erastin-induced multi-pathway cell death in endometriosis: a mechanistic and translational narrative review.

This narrative review examines the therapeutic potential of Erastin and its derivatives for endometriosis (EMS) by integrating mechanistic, preclinical, and translational perspectives. We conducted a focused review of literature from …

Published: Sept. 10, 2025, midnight
Risk of Abortion and Ectopic Pregnancy in Women with a History of Polycystic Ovary Syndrome: A Nationwide Population-Based Cohort Study.

Objectives: The purpose of this retrospective cohort study was to ascertain the risk of abortion, ectopic pregnancy and hydatidiform mole development in women with polycystic ovary syndrome (PCOS) using data …

Published: Sept. 7, 2025, midnight
Elevating and empowering reproductive futures: Pediatric and adolescent gynecology's specialized care across the globe.

Pediatric and adolescent gynecology (PAG) is an expanding subspecialty of obstetrics and gynecology that addresses the reproductive health needs of girls and young women worldwide. In regions with limited subspecialist …

Published: Sept. 5, 2025, midnight
Oxidative DNA damage may promote the development of endometriosis by activating telomerase and extending telomere length: a meta-analysis.

To investigate the associations between oxidative DNA damage biomarkers [levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), telomere length (TL), human telomerase reverse transcriptase (hTERT), telomerase activity (TA) and polymorphisms of human 8-oxoguanine glycosylase …

Published: Sept. 4, 2025, midnight
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