To explore the genetic associations between 91 types of blood cells (BCs) and endometriosis (EMs), providing references for the treatment of EMs. Forward Mendelian randomization (MR) analysis was conducted with …
NHS online hospital to focus on nine conditions – including prostate, menstrual and eye problems PublicTechnology
Fibrosis is a defining feature of endometriosis (EMS). Our previous single-cell RNA sequencing (scRNA-seq) revealed myofibroblasts (MFBs) as the predominant cells in ectopic endometrium (ECE), mainly derived from fibroblast-to-myofibroblast transition …
Endometriosis (EMs) is a common gynecological disorder associated with infertility. EMs patients often require assisted reproductive technology (ART) but exhibit lower success rates. This study aimed to characterize the follicular …
Endometriosis and adenomyosis are prevalent chronic inflammatory conditions that significantly impact reproductive-age women, leading to debilitating symptoms such as pelvic pain, dysmenorrhea, and infertility. Endometriosis is characterized by ectopic endometrial …
Studies indicate that endometriosis (EMs) is associated with inflammation and metabolic abnormalities. The Remnant Cholesterol Inflammatory Index (RCII) concurrently reflects both inflammatory and metabolic status. However, the relationship between RCII …
This study investigateted the malignant transformation of endometriosis (EMS) into ovarian clear cell carcinoma (OCCC) using spatial transcriptomics and single-cell RNA sequencing (scRNA-seq) integration. Tissues with coexisting EMS and OCCC …
Pharmacogenetics is an emerging discipline that explores how genetic variants affect drug response, potentially leading to side effects or treatment failure. Although widely applied in other medical specialties, its use …
Three-dimensional (3D) culture systems provide physiologically relevant models that better replicate in vivo cell architecture and function compared to the conventional two-dimensional cultures. In reproductive biology, 3D models of endometrial …
'A new world is coming': Plans for NHS 'online hospital’ to tackle prostate problems and menopause unveiled - here's when the new service is due to be available for patients …