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Economic evaluation of a digital symptom checker for endometriosis using a Markov decision process model.

Digital symptom checkers (SCs) are increasingly used to support early symptom recognition and care-seeking, yet evidence on their cost-effectiveness remains limited. We conducted an economic evaluation of a digital SC …

Published: March 2, 2026, midnight
Detecting the body's reproductive hormonal brake against tissue overgrowth: Micrin/SgII-70.

A new humoral factor has been detected, within a project aiming to disclose the body's reproductive hormonal brake against tissue overgrowth, micrin ('my-crin'). Factor purification involved fractionation of ovine and …

Published: March 2, 2026, midnight
Mechanism study of phthalate exposure promoting endometriosis: Based on the ferroptosis perspective.

Phthalates (PAEs), typical endocrine-disrupting chemicals (EDCs) that accumulate in the human body to induce reproductive toxicity, have epidemiological links to endometriosis (EM), but the underlying micro-mechanisms remain unclear. Ferroptosis is …

Published: March 2, 2026, midnight
Bladder Endometriosis Resolved by Robotic-Assisted Partial Cystectomy.

This is a case report of a 31-year-old G1P1 with deep infiltrating endometriosis (DIE) of the bladder. She presented with bladder spasms, dysuria, and urinary frequency that worsened during her …

Published: March 2, 2026, midnight
Establishment of a xenograft model of endometriosis-associated fibrosis using human immortalized endometrial stromal cells overexpressing HOXC8.

Endometriosis is a disease characterized by fibrosis and adhesions. There are still no treatment methods targeting these conditions. One reason for this is the lack of useful animal models to …

Published: Feb. 27, 2026, midnight
Stromal cell-derived itaconate promotes endometriosis via macrophage NRF2 and lysosomal pH modulation.

Endometriosis (EM) is driven by immune dysregulation and macrophage dysfunction, yet the underlying mechanisms remain unclear. Here, metabolomic profiling revealed excessive itaconate accumulation in EM lesions, primarily due to elevated …

Published: Feb. 27, 2026, midnight
The inhibition of deep peritoneal endometriosis by Andrographolide through macrophage M1 activity in an endometriosis mice model.

This study aims to demonstrate that Andrographolide, an herbal immunostimulant, can influence M1 macrophages to inhibit inflammation, including the growth of endometriosis caused by inflammation. This study evaluates the effects …

Published: Feb. 27, 2026, midnight
Association between history of fertility problems and pregnancy and birth complications: A longitudinal population-based cohort study.

Infertility is a common reproductive health issue, associated with increased risks of pregnancy complications. However, shared underlying risk factors such as age, BMI, PCOS, endometriosis, and lifestyle may partly explain …

Published: Feb. 26, 2026, midnight
Sexual Quality of Life after vNOTES surgery: a systematic literature review.

To systematically review the literature on women's sexual quality of life after Transvaginal Natural Orifice Endoscopic Surgery (vNOTES) for gynecological and non-gynecological procedures, and to assess women's perceptions of vNOTES, …

Published: Feb. 26, 2026, midnight
Preliminary Experience of Robotic Endometriosis From a Tertiary Care Center in India: The Learning Curve.

Background Endometriosis often requires surgery, especially in deep-infiltrating cases unresponsive to medical therapy. This study presents our institutional experience with robotic-assisted surgery (RAS) for endometriosis in Indian patients. Methodology This …

Published: Feb. 26, 2026, midnight
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