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Endometriosis and Cytoskeletal Remodeling: The Functional Role of Actin-Binding Proteins.

Endometriosis is a chronic, estrogen-dependent gynecological disorder characterized by the presence of endometrial-like tissue outside the uterine cavity. Despite its prevalence and significant impact on women's health, the underlying mechanisms …

Published: Feb. 28, 2025, midnight
Can Anticancer Drugs Be A Promising Candidate for The Treatment of Endometriosis?

Endometriosis, a benign gynecological disorder affecting 10-15% of women during their reproductive years, is characterized by the growth of endometrial tissue outside the uterus. Despite its prevalence, the exact pathophysiology …

Published: Feb. 23, 2025, midnight
Endometriosis: A new perspective on epigenetics and oxidative stress.

As a complex chronic gynecological disorder characterized by multifaceted etiology involving genetics, environment, immunity and inflammation, endometriosis (EM) has long been a significant concern for women of reproductive age worldwide. …

Published: Feb. 21, 2025, midnight
PARP-2 acts on ILK signaling and pharmacological targeting of PARP-2 ameliorate endometriosis in a mouse model.

Endometriosis, an endocrine disorder in reproductive-aged women with an occurrence of ∼10 %, gives rise to inflammation, pelvic pain, menstrual irregularity, infertility, etc. One study demonstrated the elevated plasma level …

Published: Feb. 20, 2025, midnight
CXCL14 regulates ovarian endometriosis progression by targeting PCNA.

To explore the regulatory function and mechanism of CXCL14 in endometriosis.

Published: Feb. 15, 2025, midnight
Bringing Endometriosis to the Road of Contemporary Pain Science.

Endometriosis pain is mainly understood based on peripheral lesion characteristics and an outdated perspective equating nociception with pain. This limited view may divert understanding of interventions beyond peripheral logic, leading …

Published: Feb. 5, 2025, midnight
Your period and your pregnancy, a cohort study of pregnant patients investigating the associations between menstruation and birth outcomes in Australia: study protocol.

Early pregnancy care involves the screening and identification of women with risk factors for adverse pregnancy outcomes, including stillbirth or preterm birth, to tailor pregnancy care and interventions accordingly. Most …

Published: Jan. 22, 2025, midnight
A cRGD-modified liposome for targeted delivery of artesunate to inhibit angiogenesis in endometriosis.

Currently, hormonal therapy for endometriosis faces challenges in achieving a balance between treatment and preserving the chance of pregnancy. Therefore, the development of non-hormonal therapy holds significant clinical importance. Angiogenesis …

Published: Jan. 20, 2025, midnight
Selective progesterone receptor modulators for the treatment of dysmenorrhea: an update.

Dysmenorrhea is a painful symptom associated with uterine contractions and menstrual bleeding and is treated by administering analgesic drugs. Since progesterone receptors (PRs) have a major role in regulating uterine …

Published: Jan. 14, 2025, midnight
Prevalence of anhedonia in women with deep endometriosis.

Anhedonia, characterized by diminished motivation and pleasure sensitivity, is increasingly recognized as prevalent among patients with chronic pain. Deep Endometriosis (DE), the most severe endophenotype of the disease, is commonly …

Published: Jan. 4, 2025, midnight
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