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Selective Appendectomy in Patients Undergoing Minimally Invasive Surgery for Endometriosis: A Retrospective Cohort Study.

Background/Objectives: Endometriosis is a chronic inflammatory systemic disease that commonly affects bowel structures, including the appendix, where it may mimic or coexist with chronic appendicitis. Visual inspection alone often fails …

Published: Oct. 15, 2025, midnight
Novel applications of gene and cell therapies in the treatment of gynecological disorders.

Gynecologic disorders, such as cervical and ovarian tumors, uterine fibroids, and endometriosis, present significant clinical challenges due to frequent recurrence, emerging chemoresistance, and undesirable effects associated with prolonged hormonal treatments. …

Published: Oct. 8, 2025, midnight
Extracellular Vesicles Identified as Mediators Between Endometrial Cancer Cells and Tumor-Associated Macrophages - geneonline.com

Extracellular Vesicles Identified as Mediators Between Endometrial Cancer Cells and Tumor-Associated Macrophages geneonline.com

Published: Oct. 7, 2025, 8:36 a.m.
From menses to ovulation: the immunomodulatory role of monocyte cytokines in menstrual cycle physiology and reproductive health - a narrative review.

Monocytes, as essential components of the immune system, play a pivotal role in regulating immune responses throughout the menstrual cycle. Their cytokine secretion is integral to immune modulation, influencing processes …

Published: Oct. 7, 2025, midnight
The dual nature of immunotherapy in female reproductive disorders: immune homeostasis and clinical challenges.

The female reproductive system (FRS) exhibits unique immunological characteristics, balancing defense against pathogens with tolerance to sperm and semi-allogeneic embryos. Key players include decidual natural killer (dNK) cells, immune checkpoint …

Published: Oct. 2, 2025, midnight
Targeting angiogenesis: Effects and mechanisms of action of ginsenosides.

Angiogenesis is a key link in a variety of physiological and pathological processes and plays a crucial role in tissue repair, tumor growth and ischemic diseases. Ginsenosides, as the main …

Published: Oct. 1, 2025, midnight
Systemic Immune and Tumor Marker Profiles in Ovarian and Deep Infiltrating Endometriosis: Associations with Disease Severity and Symptom Burden.

Endometriosis is a chronic, estrogen-dependent inflammatory disease with heterogeneous clinical manifestations and uncertain systemic immune involvement. This study aimed to characterize peripheral immune profiles and circulating tumor markers in women …

Published: Oct. 1, 2025, midnight
Saussurea lappa enhances folliculogenesis by suppressing F2-isoprostane, TNF-α, and apoptosis in endometriosis mice.

Endometriosis can disrupt folliculogenesis due to elevated levels of pro-inflammatory cytokines, free radicals, and the apoptotic response in granulosa cells (GCs). It can cause fertility issues in women. To date, …

Published: Sept. 30, 2025, midnight
Big data analysis reveals miR-874 as a suppressor and therapeutic target in the progression from endometriosis to ovarian cancer.

Published: Sept. 26, 2025, midnight
Mesenchymal stem cells: opening a new chapter in the treatment of gynecological diseases.

In recent years, mesenchymal stem cells (MSCs) have garnered significant attention as promising therapeutic tools for various diseases. To date, over ten MSC-based therapies have been approved and marketed worldwide, …

Published: Sept. 26, 2025, midnight
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