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RNA modifications in female reproductive physiology and disease: emerging roles and clinical implications.

RNA modifications, collectively known as the epitranscriptome, represent the third layer of gene regulation, influencing gene expression at transcriptional, post-transcriptional, and translational levels. RNA-modifying proteins (RMPs), including writers, erasers, and …

Published: March 27, 2025, midnight
PCDD/Fs in human tissues: A review of global biomonitoring data.

This review investigates the concentrations of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in internal human organs and tissues - excluding blood - with a particular focus on adipose tissue studies conducted …

Published: March 27, 2025, midnight
[Colorectal endometriosis surgery: Technical and technological innovations in service of a complex surgery].

Digestive endometriosis represents the most common form of deep endometriosis, significantly impacting patients' quality of life. The optimization of its surgical management has been marked by major technological advances. This …

Published: March 27, 2025, midnight
Endometriosis Severity and Risk of Preeclampsia: A Combined Mendelian Randomization and Observational Study.

Endometriosis has been hypothesized to increase the risk of preeclampsia (PE) and eclampsia, although the exact mechanism of this relationship is not clear. This study aimed to further explore the …

Published: March 27, 2025, midnight
Transcription factor addictions: exploring the potential Achilles' Heel of endometriosis.

A considerable number of women of reproductive age suffer from endometriosis worldwide. There is a significant physical, mental, and financial burden on patients affected by this condition in terms of …

Published: March 27, 2025, midnight
Immunopathology of Endometriosis, Molecular Approaches.

Endometriosis (EMS) is a common chronic gynecological disorder affecting 5%-10% of reproductive-age women, often causing infertility, dyspareunia, pain, and limitations in physical and sexual activities. This condition is defined by …

Published: March 26, 2025, midnight
A novel senotherapeutic strategy with azithromycin for preventing endometriosis progression.

Endometriosis is an estrogen-dependent chronic inflammatory disease, however the mechanisms underlying inflammation remain unclear. Non-hormonal drugs that can prevent endometriosis progression and resolve endometriotic infertility are urgently required. We thus …

Published: March 26, 2025, midnight
A new perspective on endometriosis: Integrating eQTL mendelian randomization with transcriptomics and single-cell data analyses.

Endometriosis is caused by the migration of endometrial cells to locations outside the uterine lining. Despite the increasing prevalence of endometriosis, there has been limited research on genetic effects, and …

Published: March 26, 2025, midnight
Recent trends in the causation of peritoneal mesothelioma: fiber burden analysis of ten cases.

Mesothelioma in the past has been strongly associated with a history of asbestos exposure. Studies have shown that, on average, a higher dose of asbestos exposure is required for the …

Published: March 26, 2025, midnight
Risk factors for recurrent implantation failure as defined by the European Society for Human Reproduction and Embryology.

What are the unrecognized risk factors for recurrent implantation failure (RIF) as defined in the ESHRE recommendation?

Published: March 26, 2025, midnight
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