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In Vivo Shadows and In Vitro Light: The Early Embryological Journey Amid Endometriosis.

Endometriosis significantly impacts fertility through complex mechanisms. These include chronic inflammation, oxidative stress, and anatomical distortion. These mechanisms impair oocyte quality, embryo development, and implantation. While in vivo challenges persist, …

Published: July 29, 2025, midnight
IVF/ICSI or surgery as first approach for the treatment of infertility associated with ovarian and deep infiltrating endometriosis? A systematic review and meta-analysis.

This systematic review and meta-analysis (CRD42024588171) compared the effectiveness of surgery followed by IVF/intracytoplasmic sperm injection (IVF/ICSI) with direct IVF/ICSI (i.e. without previous surgery) on the reproductive outcomes of infertile …

Published: July 29, 2025, midnight
Linzagolix - new perspectives in the pharmacotherapeutic management of uterine fibroids and endometriosis.

Uterine fibroids and endometriosis are among the most common conditions encountered in gynaecological practice. Fibroids affect 30-70% of women, with up to half experiencing symptoms that significantly impair quality of …

Published: July 28, 2025, midnight
The Role of MRI in Diagnosis and Pre-Surgical Mapping of Endometriosis.

Endometriosis is a chronic multisystem disease caused by the presence of endometrium-like tissue outside the endometrial canal, inciting inflammation and fibrosis. Transvaginal ultrasound (TVUS) and MRI have replaced diagnostic laparoscopy …

Published: July 28, 2025, midnight
Mapping deep endometriosis in patients with ovarian endometriomas according to the #Enzian classification: a single-center retrospective analysis.

Endometriosis is a multifactorial disease that affects mainly women of reproductive age. It is unclear whether each form of pelvic endometriosis is an independent entity and whether a spatial relationship …

Published: July 25, 2025, midnight
The Great Mimicker: Extragonadal Endometriosis Presenting as an Appendiceal Mass and Acute Appendicitis.

A 45-year-old female presented to the Emergency Department with acute right lower quadrant (RLQ) pain. Her past medical history was significant for heavy menstrual bleeding and moderate dysmenorrhea, though a …

Published: July 25, 2025, midnight
Association Between Dysmenorrhea and Endometrial Cancer: A Mendelian Randomization Study.

Background: Dysmenorrhea is a common gynecological symptom among reproductive-aged women, associated with substantial pain and decreased quality of life. Previous studies have suggested that inflammatory and hormonal fluctuations linked to …

Published: July 23, 2025, midnight
Disparities in Racial and Ethnic Representation in Clinical Trials for FDA-Approved Treatments of Endometriosis.

Published: July 23, 2025, midnight
Factors contributing to the delayed diagnosis of endometriosis-a systematic review and meta-analysis.

Endometriosis is a prevalent gynecological disorder that is estimated to affect approximately 10% of women of childbearing age globally. However, the condition remains significantly under-or misrecognized, and the mean time …

Published: July 22, 2025, midnight
A Case of Intramural Adenosarcoma With Sarcomatous Overgrowth Associated With Adenomyosis and Endometriosis.

Adenosarcoma is a mixed epithelial and mesenchymal neoplasm composed of a malignant mesenchymal component and a benign Müllerian glandular component. Although the endometrium is the most common primary site, adenosarcoma …

Published: July 21, 2025, midnight
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