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The Nexus of Iron, Senescence, and Fibrosis in Endometriosis: A Narrative Review.

Endometriosis is a prevalent chronic inflammatory condition impacting 5-10% of reproductive-age women, commonly resulting in debilitating pelvic pain and infertility. Despite extensive research efforts, the precise underlying pathophysiology remains largely …

Published: Oct. 27, 2025, midnight
Iron overload-induced ferroptosis in CD8+ T cells leads to functional abnormalities that promote endometriosis progression.

Endometriosis (EM) exhibits localised iron overload. However, the contribution of ferroptosis to EM pathogenesis remains unclear. We investigated how iron overload affects CD8⁺ T cell immune function and the underlying …

Published: Oct. 27, 2025, midnight
RND3 Inhibits Endometriosis Progression by Regulating Autophagy and Oxidative Stress Through PLEKHG5.

Endometriosis (EMS) is a chronic gynecological disease. RND3 is recognized as a potential autophagy-related biomarker in EMS. The aim of this study was to investigate the regulatory role of RND3 …

Published: Oct. 26, 2025, midnight
Ferroptosis in the Ovarian Follicular Microenvironment: A Redox-Dependent Cell Death Pathway with Emerging Roles in PCOS, Oocyte Quality, and IVF Outcomes.

Ferroptosis is a novel kind of regulated cell death that occurs when redox equilibrium is disrupted, leading to iron-dependent lipid peroxidation. Ferroptosis is defined by the buildup of deleterious lipid …

Published: Oct. 25, 2025, midnight
Quanta Therapeutics Presents Positive Phase 1 Data for QTX3034, an Oral G12D-Preferring Multi-KRAS Inhibitor, in Patients with Advanced Solid Tumors - The Manila Times

Quanta Therapeutics Presents Positive Phase 1 Data for QTX3034, an Oral G12D-Preferring Multi-KRAS Inhibitor, in Patients with Advanced Solid Tumors The Manila Times

Published: Oct. 24, 2025, 3:57 p.m.
Is systemic inflammation associated with reduced ovarian reserve in endometriosis? An investigation of anti-Müllerian hormone and inflammatory markers.

To examine the correlation between levels of anti-Müllerian hormone (AMH)-which serves as an indicator of ovarian reserve-and inflammation markers in women with endometriomas.

Published: Oct. 24, 2025, midnight
KEYTRUDA + LENVIMA shows durable 5-year survival benefit in advanced endometrial cancer - Indian Pharma Post

KEYTRUDA + LENVIMA shows durable 5-year survival benefit in advanced endometrial cancer Indian Pharma Post

Published: Oct. 22, 2025, 5:03 p.m.
Cedars-Sinai Expert Discusses Endometriosis and Fibroids - Cedars-Sinai

Cedars-Sinai Expert Discusses Endometriosis and Fibroids Cedars-Sinai

Published: Oct. 22, 2025, 4 p.m.
‘It’s not just cramps’: Women forced to seek endometriosis treatment privately amid long NHS waiting times - Suffolk News

‘It’s not just cramps’: Women forced to seek endometriosis treatment privately amid long NHS waiting times Suffolk News

Published: Oct. 22, 2025, 4 a.m.
Honokiol inhibits cell migration and invasion by blocking EMT via Snail/Slug axis in endometriosis.

Endometriosis, a common gynecological disease, leads to dysmenorrhea and infertility. EMT process was closely related to the pathology of endometriosis. More therapies were required to be explored for endometriosis management. …

Published: Oct. 22, 2025, midnight
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