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Integrated bioinformatics analysis and machine learning identifies FZD4, SRPX2, and COL8A1 as angiogenesis hub genes in endometriosis.

This study aims to identify angiogenesis-associated genes (AAGs) in endometriosis (EM) by integrating bioinformatics analysis with machine learning, and to investigate their underlying mechanisms. Differentially expressed genes (DEGs) were screened …

Published: Oct. 26, 2025, midnight
The association between HPV infection and endometriosis: Risk and fertility outcomes.

While infections have been implicated in endometriosis pathogenesis, the role of human papillomavirus (HPV) remains unclear. This study combined a meta-analysis of seven studies with a case-control study ( n …

Published: Oct. 25, 2025, midnight
Serum Galectin-1 as a Diagnostic Biomarker in Endometriosis: A Prospective Longitudinal Study.

Endometriosis is a chronic condition characterized by the presence of endometrial-like tissue outside the uterine cavity. It affects ~10% of reproductive-aged individuals and is associated with dysmenorrhea and infertility. Although …

Published: Oct. 25, 2025, midnight
Ferroptosis in the Ovarian Follicular Microenvironment: A Redox-Dependent Cell Death Pathway with Emerging Roles in PCOS, Oocyte Quality, and IVF Outcomes.

Ferroptosis is a novel kind of regulated cell death that occurs when redox equilibrium is disrupted, leading to iron-dependent lipid peroxidation. Ferroptosis is defined by the buildup of deleterious lipid …

Published: Oct. 25, 2025, midnight
Research progress and potential therapeutic targets of a novel disulfide stress-driven cell death-disulfidptosis in gynecological tumors and other gynecological disorders.

Disulfidptosis is a novel Nicotinamide Adenine Dinucleotide Phosphate (NADPH) deficiency-driven cell death pathway characterized by cystine overload and aberrant disulfide bond formation in actin cytoskeletal proteins, distinct from apoptosis, ferroptosis, …

Published: Oct. 25, 2025, midnight
Correction: Endometrial cancer (EC) derived G3BP1 overexpression and mutant promote EC tumorigenesis and metastasis via SPOP/ERα axis - Cell Communication and Signaling

Correction: Endometrial cancer (EC) derived G3BP1 overexpression and mutant promote EC tumorigenesis and metastasis via SPOP/ERα axis Cell Communication and Signaling

Published: Oct. 24, 2025, 12:50 p.m.
HMGB-1 Increases Proinflammatory Reaction via TLR4 in Human Granulosa Cells of Endometriosis.

Background/Objectives: Oxidative stress is a critical factor in the development and progression of endometriosis. Granulosa cells, which reside near oocytes in follicles, exhibit steroidogenic activity, and, consequently, influence oocyte quality. …

Published: Oct. 24, 2025, midnight
Shared Genetic Architecture Between Endometriosis and Psychiatric Conditions May Explain Comorbidity.

Endometriosis is a common chronic gynecological disorder with complex and poorly understood etiology and no definitive cure. Beyond pain and infertility, affected individuals frequently experience psychiatric comorbidities, often attributed to …

Published: Oct. 24, 2025, midnight
Genetics or geography? Australia is a global leader in polycystic ovary syndrome rates - MSN

Genetics or geography? Australia is a global leader in polycystic ovary syndrome rates MSN

Published: Oct. 23, 2025, 6:22 a.m.
PCOS: Genetics or geography? Australia is a global leader in polycystic ovary syndrome rates - The Sydney Morning Herald

PCOS: Genetics or geography? Australia is a global leader in polycystic ovary syndrome rates The Sydney Morning Herald

Published: Oct. 23, 2025, 4:41 a.m.
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