Is systemic inflammation associated with reduced ovarian reserve in endometriosis? An investigation of anti-Müllerian hormone and inflammatory markers.
To examine the correlation between levels of anti-Müllerian hormone (AMH)-which serves as an indicator of ovarian reserve-and inflammation markers in women with endometriomas.
Effects of hormonal treatment on the expression of collagen type I, matrix metalloproteinase-1, and tissue inhibitor of metalloproteinases-1 in endometriosis.
Endometriosis is an estrogen-dependent disease, and hormonal treatment is the most common treatment. Both deep infiltrating endometriosis (DIE) and ovarian endometrioma (OV) are characterized by dense surrounding fibrotic tissue. However, …
HMGB-1 Increases Proinflammatory Reaction via TLR4 in Human Granulosa Cells of Endometriosis.
Background/Objectives: Oxidative stress is a critical factor in the development and progression of endometriosis. Granulosa cells, which reside near oocytes in follicles, exhibit steroidogenic activity, and, consequently, influence oocyte quality. …
Shared Genetic Architecture Between Endometriosis and Psychiatric Conditions May Explain Comorbidity.
Endometriosis is a common chronic gynecological disorder with complex and poorly understood etiology and no definitive cure. Beyond pain and infertility, affected individuals frequently experience psychiatric comorbidities, often attributed to …
Fragility index analysis for robustness of evidence in randomized controlled trials leading to the US Food and Drug Administration approval of pharmacological therapies for endometriosis.