Enhancing aesthetic outcomes in primary umbilical endometriosis: Novel four-flap neoumbilicoplasty with case insights and comprehensive literature review.
Primary umbilical endometriosis (PUE) is a rare form of extragenital endometriosis, accounting for only 0.5%-1% of all endometriosis cases. Surgical excision is the primary treatment; however, it often results in …
Mechanism of FBXW7 mRNA degradation mediated by circSMAD2 through METTL3-METTL14 m6A axis affects proliferation and invasion of endometrial stromal cells.
This study investigates the role of circSMAD2 in ectopic endometrium of endometriosis (EMS) patients, focusing on its upregulation of FBXW7 m6A level by mediating the formation of the METTL3/METTL14 complex. …