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Ghrelin's potential as a therapeutic target for chronic inflammatory diseases: evidence from human endometrial stromal cells.

Ghrelin, a peptide composed of 28 amino acids, is recognized for its role in regulating appetite and energy balance. Recently, it has also been identified as an immunomodulator that could …

Published: Sept. 1, 2025, midnight
Application of ultrasound in combination with other methods in gynecological disease: artificial intelligence, surgery, and drugs.

Gynecological diseases (GyD) are related to reproductive tissue disorders such as the cervix, vagina, fallopian tubes, and ovaries, which can affect fertility. Among these diseases, we can mention endometriosis, ovarian …

Published: Sept. 1, 2025, midnight
Regulatory Roles of MicroRNAs in Female and Male Human Reproduction: A Narrative Review.

The role of microRNAs (miRNAs) in human reproduction represents an area of research, as these regulatory molecules appear to play essential roles in reproductive function. However, the current understanding of …

Published: Sept. 1, 2025, midnight
Differential life cycle toxic effects and molecular mechanisms of Di(2-ethylhexyl) phthalate (DEHP) exposure on the female reproductive system.

Di(2-ethylhexyl) phthalate (DEHP), the most prevalent plasticizer worldwide, can enter the human body via various exposure pathways, including ingestion, inhalation, skin contact, and medical applications. It has been observed to …

Published: Aug. 31, 2025, midnight
Adenomyosis-associated uterine rupture and pulmonary endometriosis mimicking advanced-stage uterine malignancy in an adolescent female: A case report.

Uterine adenomyosis and pulmonary endometriosis are exceptionally rare in adolescents and can pose significant diagnostic challenges due to their nonspecific clinical presentation and imaging features, which may mimic malignancy. Here, …

Published: Aug. 30, 2025, midnight
First Presentation of Endometriosis: A Case of Acute Large Bowel Obstruction.

The first presentation of endometriosis as acute large bowel obstruction is rare. We present the case of a woman in her 40s with no significant past medical history presenting with …

Published: Aug. 30, 2025, midnight
Development and validation of a postpartum cardiovascular disease risk prediction model in women incorporating reproductive and pregnancy-related predictors.

Each year, over 700,000 pregnancies occur in the UK, with up to 10% affected by complications such as hypertensive disorders of pregnancy and gestational diabetes mellitus. Pregnancy-related complications and reproductive …

Published: Aug. 29, 2025, midnight
Longitudinal association between dysmenorrhoea in adolescence and chronic pain in adulthood: a UK population-based study.

Dysmenorrhoea affects many adolescents and often goes untreated for various sociocultural reasons. Dysmenorrhoea frequently co-occurs with other chronic pain conditions, and adult women with dysmenorrhoea have greater sensory sensitivity compared …

Published: Aug. 29, 2025, midnight
Neuroinflammation is responsible for pain in endometriosis - targeting the JAK-STAT pathway and mast cell activation.

Chronic pain is a defining feature of endometriosis and contributes significantly to the diminished quality of life observed in affected individuals. Despite advances in understanding disease pathology, current therapeutic strategies …

Published: Aug. 29, 2025, midnight
Shaofu Zhuyu Decoction for Treating Endometriosis: A Systematic Review and Meta-Analysis.

Introduction: Shaofu Zhuyu Decoction (SZD) is a traditional Chinese herbal formula commonly used for gynecological disorders involving "blood stasis" and lower abdominal pain. Although applied clinically for endometriosis, evidence regarding …

Published: Aug. 29, 2025, midnight
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