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Effectiveness of BMMSC and Dienogest on IL-1β, IL-8 Expression and Lesion Area in Endometriosis Mice.

Endometriosis is a chronic estrogen-dependent inflammatory disease that impairs fertility and quality of life. Dienogest, the current standard therapy, provides symptom relief but does not correct immune imbalance or prevent …

Published: March 17, 2026, midnight
Repeatedly occurring retrograde menstruation intensifies central sensitization driven by neuroinflammation in endometriosis models.

This study investigated how chronic pelvic pain (CPP) develops using rhesus macaques with naturally occurring endometriosis and a multiple-lesion induction mouse model (MIM), as repeated retrograde menstruation is considered an …

Published: March 17, 2026, midnight
Efficacy of probiotic supplementation in reducing primary dysmenorrhea: a double-blinded randomized controlled trial.

Primary dysmenorrhea is painful menstruation in the absence of pelvic pathology, whereas secondary dysmenorrhea is menstrual pain attributable to an underlying pelvic disease (e.g., endometriosis). Nonsteroidal anti-inflammatory drugs (NSAIDs) are …

Published: March 17, 2026, midnight
Intraoperative Transvaginal Ultrasound for Rectosigmoid Endometriosis: A Feasibility Study.

Published: March 17, 2026, midnight
Xanthogranulomatous Oophoritis Associated With Chronic Endometriosis: A Clinical Observation.

Xanthogranulomatous oophoritis (XGO) is a rare chronic inflammatory con-dition that can mimic ovarian malignancy both clinically and radiologically. It is characterized by foamy histiocytes and inflammatory infiltrates, often leading to …

Published: March 17, 2026, midnight
Safety and Reproductive Outcomes of Minimally Invasive Nerve-Sparing Surgery for Deep Endometriosis in Infertile Women: A One-Year Follow-Up Study.

Background/Objectives: Deep endometriosis is a chronic inflammatory disease that significantly affects fertility. The objective was to evaluate the magnitude of the effect of minimally invasive nerve-sparing complete excision of endometriosis …

Published: March 17, 2026, midnight
Exploring endometriosis through 3D in vitro models: A narrative review.

Endometriosis is a prevalent inflammatory disease affecting approximately one in ten women, characterized by endometrial tissue outside the uterus. Despite its high incidence, treatment options are limited, and the underlying …

Published: March 17, 2026, midnight
Minimally Invasive Management of a Mullerian Anomaly: A Clinical Decision-Making Tree.

To describe the presentation and management of a symptomatic Müllerian duct abnormality in a teenager and propose an evidence based clinical decision-making tree on when to treat based on a …

Published: March 16, 2026, midnight
Bidirectional prospective relationship of endometriosis with major depressive disorder: the mediating role of metabolic biomarkers.

Endometriosis and major depressive disorder (MDD) pose significant global health burdens. Despite pathophysiological overlaps, existing epidemiological studies predominantly examine their unidirectional associations, often constrained by cross-sectional designs and small sample …

Published: March 16, 2026, midnight
Uterine Anteroposterior Diameter as an Imaging Correlate of Dysmenorrhea Severity: Findings Across Symptom Based Clusters.

Adenomyosis and endometriosis are both recognized as etiological factors in the development of dysmenorrhea; however, their respective contributions to this condition remains ambiguous. This study aims to examine the distinct …

Published: March 16, 2026, midnight
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