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Integrative microbiome-metabolomics identifies Pseudomonas as a potential pathogenic factor in endometriosis.

Endometriosis (EMS) is a chronic disease characterized by unclear etiology, influenced by various genetic and environmental factors, with no definitive biomarkers available for early screening. Recent studies suggest that the …

Published: Oct. 30, 2025, midnight
Risk factors for postoperative recurrence of deep infiltrating endometriosis during a 6- to 12-year follow-up.

This study aimed to identify risk and protective factors for postoperative recurrence of deep infiltrating endometriosis (DIE). We analyzed 320 patients undergoing laparoscopic excision with ≥ 6 years follow-up at …

Published: Oct. 28, 2025, midnight
The Nexus of Iron, Senescence, and Fibrosis in Endometriosis: A Narrative Review.

Endometriosis is a prevalent chronic inflammatory condition impacting 5-10% of reproductive-age women, commonly resulting in debilitating pelvic pain and infertility. Despite extensive research efforts, the precise underlying pathophysiology remains largely …

Published: Oct. 27, 2025, midnight
Serum Galectin-1 as a Diagnostic Biomarker in Endometriosis: A Prospective Longitudinal Study.

Endometriosis is a chronic condition characterized by the presence of endometrial-like tissue outside the uterine cavity. It affects ~10% of reproductive-aged individuals and is associated with dysmenorrhea and infertility. Although …

Published: Oct. 25, 2025, midnight
Impact of Minimally Invasive Surgery on Quality of Life and Infertility in Deep Infiltrating Endometriosis.

Background: Endometriosis is a chronic, estrogen-dependent inflammatory disease affecting up to 10% of women of reproductive age. It substantially impacts quality of life (QoL) through pelvic pain, infertility, and psychological …

Published: Oct. 14, 2025, midnight
Identification and Validation of Iron Metabolism-Related Biomarkers in Endometriosis: A Mendelian Randomization and Single-Cell Transcriptomics Study.

Studies have shown that the iron concentration in the peritoneal fluid of women is associated with the severity of endometriosis. Therefore, investigation of iron metabolism-related genes (IM-RGs) in endometriosis holds …

Published: Oct. 9, 2025, midnight
Does age influence surgical technique in bowel endometriosis? A multicenter analysis of 1547 cases.

To evaluate whether patient age influences the complexity of the surgical approach for bowel endometriosis, including the technique performed and the route of specimen extraction. Methods: Retrospective, multicenter observational study, …

Published: Oct. 7, 2025, midnight
Extracellular granzyme B and K are associated with endometriosis severity in infertile women.

Endometriosis is a chronic inflammatory condition often associated with infertility. The role of granzymes as cytotoxic proteases and immune regulators in endometriosis remains poorly understood. This study evaluated serum and …

Published: Oct. 4, 2025, midnight
Inflammatory Cytokine Signatures Are Associated With Disease Burden and Comorbidity of Episodic Migraine and Endometriosis.

The aim of this study was to characterize inflammatory cytokine profiles in women diagnosed with episodic migraine, endometriosis, or both conditions and to determine how these cytokine patterns relate to …

Published: Oct. 3, 2025, midnight
Evaluation of serum-based inflammatory and haematological markers in patients with endometriosis: A case-control study.

To assess the diagnostic value of serum-based inflammatory and haematological markers in women with endometriosis, and determine their relationship with disease severity, including lesion characteristics.

Published: Oct. 2, 2025, midnight
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