Bioinformatics-Based Identification of Differentially Expressed Genes in Endometrial Carcinoma: Implications for Early Diagnosis and Prognostic Stratification Frontiers
The endometrium is a vital mucosal tissue which undergoes cyclical regeneration, differentiation, and remodeling upon hormonal, cellular, and molecular signaling networks. Dysregulation of these processes can trigger a range of …
Background/Objectives: Rarely, primary (PriCs) or metastatic (metECs) carcinomas occur in the episiotomy site. Methods: A systematic literature review of metECs was carried out. We reviewed the PRISMA guidelines and the …
Incidental Primary Ovarian Squamous Cell Carcinoma Arising in Endometriosis Presenting As Adenomyosis-Related Abnormal Uterine Bleeding Cureus
Adenomyosis often coexists with endometriosis, which primarily involves the ovary and can lead to endometriosis‑associated ovarian cancers, most commonly endometrioid and clear‑cell carcinomas. Ovarian squamous cell carcinoma (OSCC) arising in …
This systematic review aimed to summarize all available data and evaluate the roles of E-cadherin, N-cadherin, associated molecules, and signaling pathways in the pathogenesis of endometriosis. The search was conducted …
A Lipid Metabolism and Lysosome-based Risk Signature for Prognosis and Immune Response Prediction in Uterine Corpus Endometrial Carcinoma Frontiers
The involvement of lncRNA EMSLR in the disulfidptosis and progression of endometrial carcinoma Nature
While epidemiological studies have associated endometriosis with ovarian cancer risk, the causal relationships across anatomic subtypes and histotypes remain undefined. Using two-sample Mendelian randomization with 84 genetic instruments (F-statistic = …
Synchronous Primary Vulvar Squamous Cell Carcinoma and Ciliated Cell Variant of Endometrioid Adenocarcinoma Arising in an Endometrial Polyp: A Rare Dual Malignancy Cureus