Latest Articles

M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy With Comorbid Traits.

Endometriosis is a common gynecologic condition that causes chronic, life-altering symptoms including pain and infertility. There is an urgent need for new non-hormonal targeted therapeutics to treat endometriosis, but until …

Neurotrimin, a neural adhesion molecule, expression in early and advanced stage endometriosis.

Endometriosis, a gynecological condition characterized by the presence of endometrial tissue outside the uterus, affects millions of women worldwide. This study aimed to investigate neurotrimin (NTM)'s expression, a glycerophosphatidylinositol-anchored neural …

Erastin-induced multi-pathway cell death in endometriosis: a mechanistic and translational narrative review.

This narrative review examines the therapeutic potential of Erastin and its derivatives for endometriosis (EMS) by integrating mechanistic, preclinical, and translational perspectives. We conducted a focused review of literature from …

First documented case of decidualized endometriosis on the anterior peritoneum during emergency cesarean section: a case report and literature review.

Endometriosis is a chronic gynecological condition characterized by the presence of endometrial-like tissue outside the uterine cavity. Although commonly associated with pelvic pain and infertility, its incidental discovery during a …

Correlation between the AAGL 2021 classification and the occurrence of perioperative complications in endometriosis surgery.

The AAGL 2021 classification assesses intraoperative surgical complexity using a four-stage scale based on lesion size and location. Despite its potential utility, no data currently assess its correlation with perioperative …

Correction: Blocking GATA6 Alleviates Pyroptosis and Inhibits Abdominal Wall Endometriosis Lesion Growth Through Inactivating the PI3K/AKT Pathway.

Fine-needle Aspiration Cytology of Cutaneous Endometriosis: A Series of 17 Cases with Literature Review.

Cutaneous endometriosis, a rare entity, is a type of extra pelvic endometriosis observed in 0.5%-1% of women. The most common sites include the abdominal wall, umbilicus, vulva, and extremities. It …

Dysfunction of natural killer cells promotes immune escape and disease progression in endometriosis.

Endometriosis (EMs) is a chronic inflammatory disorder characterized by dysregulated innate immunity, particularly impaired cytotoxic function of natural killer (NK) cells. As pivotal effectors of the innate immune response, NK …

Polychlorinated biphenyl Endocrine Disruptor Alters Estrogen Receptor beta-Mediated Epigenetic Regulation, Promoting Endometriosis.

Background Endometriosis is a pathological condition characterized by the ectopic proliferation of endometrial cells, resulting in chronic pelvic pain and infertility. Exposure to endocrine-disrupting chemicals (EDCs) has been implicated in …

A Survey of the Reproductive Lesions in Captive Female Non-Human Primates in Italy.

Non-human primates (NHPs) are considered important models for the study of reproductive diseases, due to their anatomical and physiological similarities to humans. However, studies on spontaneous lesions of the reproductive …