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Safety of 48 months of elagolix with add-back therapy for endometriosis-associated pain.

Elagolix (ELA) 200 mg twice daily is an oral treatment approved for moderate-to-severe endometriosis-associated pain. However, the clinical use of ELA is limited by potential hypoestrogenic effects, including the loss …

Published: Nov. 7, 2025, midnight
Real Time Nerve Mapping for Endometriosis Involving the Sciatic & Pudendal Nerves.

To demonstrate a standardized and reproducible technique utilizing intraoperative neurophysiological monitoring (IONM) with real-time nerve mapping to improve the safety of deep infiltrating endometriosis surgery and facilitate the preservation of …

Published: Nov. 6, 2025, midnight
Sonographic and Clinical Progression of Adenomyosis and Coexisting Endometriosis: Long-Term Insights and Management Perspectives.

Objectives: To evaluate the impact of hormonal therapy on the evolution of painful symptoms in premenopausal women with adenomyosis, with or without concomitant endometriosis, over an 18-month follow-up period. This …

Published: Nov. 6, 2025, midnight
Metabolome analysis as a potential source of endometriosis biomarkers with the use of multiomics approach in its diagnosis - Nature

Metabolome analysis as a potential source of endometriosis biomarkers with the use of multiomics approach in its diagnosis Nature

Published: Nov. 5, 2025, 1:30 p.m.
‘Brilliant’ smartwatch with battery life ‘way ahead of Apple and Android’ gets huge discount - Her.ie

‘Brilliant’ smartwatch with battery life ‘way ahead of Apple and Android’ gets huge discount Her.ie

Published: Nov. 5, 2025, 1:06 p.m.
Metabolome analysis as a potential source of endometriosis biomarkers with the use of multiomics approach in its diagnosis.

Endometriosis poses diagnostic challenges. This study aimed to analyze the metabolomic profiles of plasma and peritoneal fluid samples obtained from women with endometriosis compared to controls. Our multicenter study involved …

Published: Nov. 5, 2025, midnight
In vitro fertilization-assisted pregnancy combined with high-intensity focused ultrasound treatment in patients with endometriosis and adenomyosis with successful pregnancy: a case report.

High-intensity focused ultrasound ablation has emerged as a noninvasive therapeutic option for adenomyosis of the uterus. We studied a female with infertility patient to explore the application of in vitro …

Published: Nov. 5, 2025, midnight
Nanodrug impact on female reproductive health and fetal development: From translation approaches to long-term safety concern.

Biomaterials for drug delivery offer significant advantages over conventional medications, including enhanced cellular uptake, improved drug stability, targeted delivery, and controlled drug release. Cutting-edge nanodrugs delivery approaches such as drugs …

Published: Nov. 5, 2025, midnight
Inpatient Endometriosis Care in Germany: Hospital Caseloads and their Spatial Distribution.

Endometriosis is a chronic gynaecological disease with an estimated prevalence of 10-15%. The German guideline provides evidence-based recommendations for diagnosis and treatment, but care provided is inadequate care due to …

Published: Nov. 3, 2025, midnight
Novel Application of the Lagis LapBase Cap in Transvaginal NOTES Hysterectomy: Surgical Outcomes and Cost-Effectiveness in 107 Cases.

Objectives: Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) offers significant benefits in hysterectomy, including reduced postoperative pain, minimal scarring, and faster recovery. However, the cost and accessibility of surgical ports …

Published: Nov. 3, 2025, midnight
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