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Is surgery for endometriomas ever indicated?

Endometriomas can be managed through various approaches, including careful observation, medical suppressive therapy, or surgical intervention. Malignancy is rarely a concern in women of reproductive age, making pain relief and …

Published: Dec. 15, 2025, midnight
Delayed onset of HPV-associated uterine malignancies: seven pathogenetic factors in contrast to cervical cancer.

Human papillomavirus (HPV) is a well-established etiological agent for cervical cancer, yet its contribution to endometrial malignancies remains underrecognized and mechanistically distinct. This paper synthesizes current evidence to explain the …

Published: Dec. 13, 2025, midnight
[Immunology of fertilization, implantation and pregnancy: Key interactions and therapeutic perspectives].

The immunology of fertilization, implantation and pregnancy is based on a complex balance between maternal immune tolerance and a controlled inflammatory response. Adaptation of the maternal immune system is essential …

Published: Dec. 13, 2025, midnight
From Gynecological Endocrine Disorders to Cardiovascular Risk: Insights from Rat Models.

Gynecological endocrine disorders, including polycystic ovary syndrome (PCOS), endometriosis as well as primary ovarian insufficiency (POI)/premature ovarian failure (POF), significantly impact women's reproductive health and overall well-being. While these conditions …

Published: Dec. 13, 2025, midnight
The interplay between migraine, endometriosis and polycystic ovarian syndrome: A systematic review.

BackgroundMigraine and gynecological conditions, such as endometriosis (EDM) and polycystic ovarian syndrome (PCOS), are highly prevalent among females and appear to influence each other, with a potential shared pathophysiological mechanism. …

Published: Dec. 12, 2025, midnight
Research trends in estrogen and rheumatoid arthritis: a systematic bibliometric approach.

Rheumatoid arthritis (RA) is a chronic autoimmune disease. An increasing body of evidence indicates that hormones, particularly estrogen, play a significant role in RA. To date, no bibliometric studies have …

Published: Dec. 12, 2025, midnight
Burrowing behavior is a potential non-invasive proxy for lesion development in a syngeneic murine model of endometriosis.

Endometriosis (EM) is a persistent, chronic inflammatory condition associated with excruciating pelvic pain and infertility. The absence of a pre-clinical model that reliably replicates the clinical and functional hallmarks of …

Published: Dec. 12, 2025, midnight
Coexistence of gynecological pathology with endometriosis and adenomyosis.

Both endometriosis and adenomyosis can impact quality of life. Endometriosis is a chronic, benign, condition characterized by the growth of endometrium outside the uterus, which affects ~10% of women from …

Published: Dec. 12, 2025, midnight
Endometriosis Imaging Diagnosis Beyond Specialized Centers: A Retrospective Cross-Sectional Study.

Determine the accuracy of deep endometriosis (DE) and ovarian endometrioma (OE) diagnosis on pelvic MRI in non-specialized tertiary healthcare, taking surgical diagnosis as the reference test. Additionally, we aimed to …

Published: Dec. 12, 2025, midnight
Beyond waste: menstrual blood as a powerful diagnostic tool for women's health.

Menstrual blood (MB), once thought of as nothing more than biological waste, has now come to be regarded as a noninvasive and low-cost diagnostic tool with great potential for women's …

Published: Dec. 12, 2025, midnight
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