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Factors associated with breakthrough pain with labor epidural analgesia: a single-center prospective study.

Breakthrough pain requiring anesthesiologist intervention occurs in 14-55% of parturients despite labor epidural analgesia, substantially affecting the childbirth experience. Identifying predictive factors may enable more effective, individualized pain management.

Published: Oct. 14, 2025, midnight
A review of treatment options for chronic pelvic pain from endometriosis.

Chronic pelvic pain is a severe condition affecting patients with endometriosis. Treatment options range from physical therapy, medical management, to surgical resection. However, some patients continue to have severe pain …

Published: Aug. 2, 2025, midnight
The efficacy of progestins in managing pain associated with endometriosis, fibroids and pre-menstrual syndrome: a systematic review.

Alongside being contraceptives, progestins have been investigated as potential anti-inflammatory and analgesic therapies for use in painful gynaecological conditions. This review aims to synthesise evidence pertaining to the efficacy of …

Published: March 11, 2025, midnight
Identification of predictors for acute postoperative pain after gynecological laparoscopy (STROBE-compliant article).

While the pain after gynecological laparoscopy is assumed to be minor, many women suffer from unexpected postoperative pain in the post-anesthesia care unit (PACU). Prior identification of these patients is …

Published: Oct. 14, 2024, 1:26 p.m.
P2X3 and P2X2/3 Receptors Inhibition Produces a Consistent Analgesic Efficacy: A Systematic Review and Meta-Analysis of Preclinical Studies.

P2X3 and P2X2/3 receptors are promising therapeutic targets for pain treatment and selective inhibitors are under evaluation in ongoing clinical trials. Here we aim to consolidate and quantitatively evaluate the …

Published: Oct. 9, 2024, midnight
An Integrative Approach for Endometriosis-Related Pain.

Pain is a common, severe symptom related to endometriosis. Despite this prominent feature, there is limited literature regarding its description and use of integrative treatment methods.

Published: Sept. 21, 2024, midnight
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