Adenomyosis is a prevalent disorder of the archimetra, historically conflated with endometriosis but possessing a unique pathobiological trajectory. This review synthesises current molecular evidence to propose a unified mechanistic framework …
India, home to 4 biodiversity hotspots, hosts 675 wild species used for nutritional and therapeutic purposes. Wild edible fruits are highly valuable for their rich content of health-beneficial compounds, such …
The endometrium is a highly dynamic and complex tissue lining the uterus, playing a central role in reproductive health. Despite its importance, the pathogenesis of many benign endometrial disorders remains …
Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare (prevalence ~ 1:2 million), devastating genetic disorder characterized by progressive heterotopic ossification. Crucially, surgical trauma is a potent trigger for catastrophic new bone …
Ovarian cancer was the eighth most frequently diagnosed cancer among women in 2022. The global age-standardized incidence rate of ovarian cancer decreased from 7.22/100,000 to 6.71/100,000 from 1990 to 2021. …
The LYSET gene encodes the LYSET transmembrane protein, which regulates lysosome biogenesis by activating the mannose-6-phosphate (M6P) pathway. This is an autosomal recessive, ultrarare, and severe progressive skeletal dysplasia with …
Both genetic and environmental factors affect human stature, including overall height and familial short stature (FSS), and it is associated with various health outcomes. However, the study of genetic connections …
The origin of ectopic gynecologic lesions has been debated since 1927, when Sampson first proposed retrograde menstruation as the underlying cause of endometriosis. Reproduction in mammals is an unusually permissive …
Endometriosis is a common gynecological disease associated with pelvic pain and infertility. Despite several existing theories, the etiology and molecular mechanisms of endometriosis remain to be investigated. Here we report …
A rare case of primary amenorrhea caused by cervical hypoplasia and vaginal agenesis highlights the critical need for early diagnosis and timely surgical intervention to prevent severe complications such as …