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Shared genetic architecture and cellular convergence between female reproductive disorders and pulmonary function: a genome-wide cross-trait analysis.

Female reproductive disorders (FRDs), including polycystic ovary syndrome, endometriosis, uterine leiomyomata, and infertility, have been epidemiologically associated with impaired pulmonary function. However, it remains unclear whether this cross-organ link reflects …

Published: Sept. 1, 2026, midnight
Thyroid autoimmunity, thyroid function, and endometriosis: reproductive immune-endocrine crosstalk and causal uncertainty.

Endometriosis is an estrogen-dependent inflammatory disorder associated with pelvic pain, infertility, repeated treatment, and impaired quality of life. Thyroid dysfunction and thyroid autoimmunity are also common in reproductive-aged women and …

Published: Aug. 7, 2026, midnight
Associations between granulysin and ovarian endometriosis: A 2-sample Mendelian randomization study.

Endometriosis (EMS) is a chronic inflammatory disease defined by the presence of endometrial-like tissue outside the uterine cavity. Ovarian EMS is considered the most prevalent disease phenotype. However, the causal …

Published: July 19, 2026, midnight
Gut microbiota dysbiosis in endometriosis: mechanistic insights and gut microbiota-targeted therapeutic strategies.

Endometriosis (EMs) is a prevalent, estrogen-dependent gynecological disorder characterized by the ectopic implantation and proliferation of endometrial-like tissue outside the uterine cavity, affecting approximately 10% of reproductive-aged women globally. Despite …

Published: June 5, 2026, midnight
Optimizing women's cardiovascular health across the life course: The role of physical activity in female-specific conditions.

Cardiovascular disease is the leading cause of morbidity and mortality in women, and its development results from both traditional risk factors and female-specific determinants that emerge across the life course. …

Published: May 1, 2026, midnight
From lipid profiles to disease onset: Triglycerides as predictive biomarkers in endometriosis.

Dyslipidaemia is related to endometriosis, but it is not known which lipid component is most relevant, and whether the observed correlation reflects the causal relationship. The relationship between triglycerides (TG) …

Published: March 7, 2026, midnight
Unraveling the link between early sexual initiation and endometriosis: evidence from population-based analyses and genetic causal inference.

Published: March 3, 2026, midnight
Inverse association between cardiometabolic index and endometriosis in women of reproductive age: A cross-sectional, population-based study.

ObjectiveThis study aimed to investigate the relationship between the cardiometabolic index and the prevalence of endometriosis among reproductive-age women in the United States. This cross-sectional population-based study used data from …

Published: Feb. 25, 2026, midnight
Association Between Endometriosis and Atopic Dermatitis: Evidence from NHANES and Genetic Causal Inference.

Published: Nov. 27, 2025, midnight
The Role of Endometriosis in Intestinal Inflammation: A Combined Mendelian Randomization and Cellular Study.

This study aims to assess whether endometriosis causally increases the risk of IBD through Mendelian randomisation (MR) analysis and to elucidate potential mechanisms using in vitro experiments. A two-sample Mendelian …

Published: Sept. 10, 2025, midnight
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