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Systemic Immune and Tumor Marker Profiles in Ovarian and Deep Infiltrating Endometriosis: Associations with Disease Severity and Symptom Burden.

Endometriosis is a chronic, estrogen-dependent inflammatory disease with heterogeneous clinical manifestations and uncertain systemic immune involvement. This study aimed to characterize peripheral immune profiles and circulating tumor markers in women …

Published: Oct. 1, 2025, midnight
Multi-ancestry genome-wide association study of endometriosis and its clinical manifestations in ~1.4 million women: translating gene discovery into pathogenic mechanisms and therapeutic targets.

We conducted a multi-ancestry genome-wide association study of endometriosis and adenomyosis in almost 1.4 million women, including 105,869 cases, aiming to expand endometriosis loci discovery across ancestries, dissect symptom-specific effects, …

Published: Sept. 5, 2025, midnight
Research progress on the correlation between microbiota and endometriosis.

The microbiota constitutes a vital component of the human microenvironment, dynamically responding to physiological changes and playing crucial roles in maintaining normal bodily functions. Endometriosis (EMs), defined as a chronic, …

Published: Aug. 25, 2025, midnight
Non-Hormonal Strategies in Endometriosis: Targets with Future Clinical Potential.

Endometriosis is a chronic gynecological pathology marked by the aberrant proliferation of tissue analogous to the endometrial lining outside the uterine cavity. This disorder frequently engenders persistent pelvic discomfort, infertility, …

Published: July 17, 2025, midnight
Efficacy of Transvaginal Ultrasound vs Pelvic MRI in Preoperative Diagnosis of Pelvic Endometriosis.

BACKGROUND Experts and experience in the medical profession are required for diagnosis of pelvic endometriosis. The objective of this study was to compare the diagnostic parameters of transvaginal ultrasound versus …

Published: April 10, 2025, midnight
Atypical Endometriosis - An Overview of the Issue and Personal Experiences.

Endometriosis is a chronic, estrogen-dependent, inflammatory disease characterized by the growth of endometriotic tissue outside the uterus. Among the wide spectrum of clinical manifestations of endometriosis, chronic pelvic pain, dysmenorrhea, …

Published: March 17, 2025, 12:08 a.m.
Endometriosis and Infertility: Gynecological Examination Practical Guide.

Endometriosis, a prevalent gynecological condition affecting 10-15% of reproductive-age women, involves the growth of endometrial-like tissue outside the uterine cavity. This chronic inflammatory disease can significantly impact fertility by disrupting …

Published: March 12, 2025, midnight
Diagnostic accuracy of plasma microRNA as a potential biomarker for detection of endometriosis.

Endometriosis is a complex condition with a wide range of clinical manifestations, presenting significant challenges, particularly for young women. Its diverse and often perplexing presentations pose difficulties within the medical …

Published: March 7, 2025, midnight
The connection between endometriosis and secondary dysmenorrhea.

Endometriosis (EMS) is a prevalent gynecological condition characterized by the presence of endometrial tissue outside the uterus, often leading to secondary dysmenorrhea (SD), chronic pelvic pain and infertility. This review …

Published: Jan. 9, 2025, midnight
Thoracic Endometriosis Syndrome in a 75-Year-Old Woman.

Thoracic endometriosis syndrome (TES) is a rare condition where endometrial tissue is found in the pleura, parenchyma, and/or diaphragm. Haemoptysis is a common manifestation of pulmonary endometriosis and can be …

Published: Nov. 25, 2024, midnight
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