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Identification of potent inhibitors of JUN N-terminal kinases for treatment of endometriosis and associated pain.

Endometriosis, defined as the ectopic growth of endometrial tissue outside of the uterine cavity, is an inflammatory and hormone-dependent disease that causes excruciating pelvic pain, infertility, and significantly decreases quality …

Published: Aug. 19, 2026, midnight
Diet and physical activity coaching for well-being and pain reduction in patients with symptomatic endometriosis: a randomized-controlled clinical trial.

Pain is a defining symptom of endometriosis reducing quality of life and increasing the risk of psychological disorders. We conducted an open-label, randomized, controlled trial to investigate whether structured coaching …

Published: Aug. 17, 2026, midnight
Role of oral gonadotropin-releasing hormone antagonists in the management of uterine adenomyosis: a narrative review.

In women with uterine adenomyosis, bleeding and pain can have a major impact on quality of life. There is clearly widespread demand for effective long-term medical therapies. The objective of …

Published: Aug. 14, 2026, midnight
Adipose Stem Cell Mitochondrial Transplantation in ART: From Biological Rationale to Clinical Milestone.

Oocyte quality is the primary determinant of success in assisted reproductive technologies (ART), and mitochondrial dysfunction is increasingly recognized as a central mediator of poor oocyte competence across advanced maternal …

Published: Aug. 10, 2026, midnight
Activin A is a functional component of the anti-endometriotic drug Endoferin.

Endometriosis is a prevalent gynecological condition affecting up to 25-40% of women with infertility. Endoferin, a protein complex derived from the bovine ovarian follicles, has demonstrated high efficacy in clinical …

Published: July 31, 2026, midnight
Efficacy of Targeted Vasopressin Injection at the Recto-Uterine Endometrioid Lesion during Laparoscopic Surgery for Deep Infiltrating Endometriosis: A Randomized Clinical Trial.

To evaluate the efficacy of targeted vasopressin injection at the recto-uterine endometrioid lesion during laparoscopic dissection in patients with deep infiltrating endometriosis (DIE).

Published: July 30, 2026, midnight
Real-word evidence on the effectiveness of the Endo-App in reducing endometriosis-related complaints: a retrospective analysis.

Randomized controlled clinical trials have shown that symptoms of chronic pain conditions, such as endometriosis, can be improved with the use of specialized health apps. In the current study, real-world …

Published: July 27, 2026, midnight
Ethanol Sclerotherapy for Primary and Recurrent Endometrioma Improves In Vitro Fertilization Pregnancy Outcomes: A Randomized Clinical Trial.

Alcohol sclerotherapy has been shown to reduce endometrioma recurrence and improve ovarian response, including the number of retrieved oocytes and antral follicle count (AFC), compared with surgical cystectomy. This randomized …

Published: July 27, 2026, midnight
Rheumatic Heart Disease: Inflammation, Immune Pathways, Valve Remodeling, and the Promise of SGLT2 Inhibitors.

Rheumatic heart disease (RHD) remains the leading cause of acquired valvular heart disease in low- and middle-income countries, affecting an estimated 40 million individuals and disproportionately affecting children and young …

Published: July 16, 2026, midnight
Adjunctive vitamin D supplementation in women receiving dienogest therapy for endometriosis: a randomized controlled trial.

Endometriosis is a chronic, estrogen-dependent inflammatory disease that causes debilitating pain and significantly impairs quality of life. Due to its anti-inflammatory and immunomodulatory properties, vitamin D has been proposed as …

Published: July 16, 2026, midnight
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