Distinct Risk Factor and Comorbidity Profiles Tied to Endometriosis Subtypes Medscape
In 1999, Dr Susan Treloar and colleagues conducted a landmark twin study in Australia and reported their estimate of 51% for the heritability of endometriosis. This important result led several …
While endometriosis is thought to be a heterogeneous disease, the pathophysiologic heterogeneity across the three visualized lesion macrophenotypes (i.e., superficial peritoneal endometriosis(SPE) lesions, endometriomas, and deep lesions) remains unclear.
Observational studies have reported comorbidity between autoimmune thyroid disease and endometriosis, but whether this reflects a direct causal relationship or shared susceptibility remains unclear. We evaluated the bidirectional relationship between …
Uterine artery embolization (UAE) is a minimally invasive therapeutic option for adenomyosis (AM). However, its clinical effectiveness in patients with comorbid gynecologic disorders remains unclear. This study aimed to evaluate …
This study aimed to assess whether the presence of endometriosis and/or adenomyosis on advanced ultrasound accounts for variations in quality of life. Our secondary objective was to examine potential determinants …
This study aimed to systematically assess the genetic comorbidity of endometriosis (EM) and its subtypes with menstrual-cycle-related traits, and to identify shared genetic mechanisms and key regulatory pathways underlying their …
A growing body of literature has revealed that patients with endometriosis are at an increased risk for epithelial ovarian cancer (EOC) and cardiovascular disease (CVD). Endometriosis is a heterogeneous disease …
Chronic overlapping pain conditions (COPCs) refer to a set of chronic pain disorders that frequently co-occur and may involve partially overlapping mechanisms. The U.S. National Institutes of Health currently recognizes …
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a common source of chronic pelvic pain. The aim of this study was to determine the gynecologic comorbidities associated with bladder pain in the …