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Infertility currently affects nearly one in six couples, representing more than 3.3 million people in France. Infertility now occurs in an unprecedented demographic context, marked by a rapid decline in fertility: …

Published: May 23, 2026, midnight
ADVANTAGE: Advanced discovery of visceral analgesics by neuroimmune targets and the genetics of extreme human phenotype, a study protocol.

Chronic visceral pain affects over 20% of adults globally but remains poorly understood, significantly impacting quality of life and healthcare costs. Limited understanding and diagnostic misconceptions hinder effective management, particularly …

Published: May 21, 2026, midnight
Vulvar Widening Through Perineal Flap Transposition, Rigottomy, And Fat Grafting For Vulvar Lichen Sclerosus.

Vulvar lichen sclerosus (VLS) is a chronic condition. If untreated, it may lead to anatomical modifications, including introital stenosis, which may impact sexual function and quality of life. First line …

Published: May 20, 2026, midnight
Diagnosis of Endometriosis: Dual-Amplification Strategy Driven by Copper Nanoclusters.

Endometriosis is a prevalent gynecologic disorder associated with infertility and increased cancer risk, necessitating the development of sensitive and reliable diagnostic methods. Circulating microRNAs (miRNAs) have emerged as promising noninvasive …

Published: May 14, 2026, midnight
The Incidence of Negative Laparoscopy for Pelvic Pain Stratified by Level of Training and Location of Service Provision.

Systematic reduction of negative laparoscopy for pelvic pain is crucial to reducing surgical morbidity, improving diagnostic accuracy and minimising cost. This study aims to determine the incidence and consider the …

Published: May 10, 2026, midnight
Visual tubal patency tests for tubal occlusion and hydrosalpinx.

Around 18% to 33% of couples with infertility present with tubal occlusion (blocked or damaged fallopian tubes) or hydrosalpinx (fluid-filled tubes). Diagnostic laparoscopy (keyhole surgery) with chromopertubation (methylene blue dye …

Published: May 4, 2026, midnight
Evaluating Subtypes of Endometriosis in Rhesus Macaques (Macaca mulatta) Using Clinical Findings and Immunohistochemistry.

Endometriosis is defined as endometrial tissue outside of the uterus. It is a debilitating, complex, and underdiagnosed condition, impacting approximately 10%-15% of reproductive-aged women worldwide. Endometriosis is associated with chronic …

Published: April 1, 2026, midnight
Is Cross-Matching Required? Analysis of Blood Transfusion in Gynecological Surgeries at an Academic Hospital in Bangkok, Thailand: A Cross-Sectional Study.

Effective utilization of perioperative blood transfusions can reduce costs and minimize blood waste. This study aimed to audit the appropriateness of current blood utilization practices in gynecological surgeries, characterize transfusion …

Published: March 30, 2026, midnight
Decoding the Endometriosis-Associated Infertility Microenvironment: A Review of FTIR and Raman Spectroscopic Insights into Follicular Fluid.

Background: Endometriosis is a major cause of female infertility. It significantly impacts oocyte quality and embryonic development. The condition's pathophysiological mechanisms are multifactorial. However, they are believed to be reflected …

Published: March 12, 2026, midnight
Economic evaluation of a digital symptom checker for endometriosis using a Markov decision process model.

Digital symptom checkers (SCs) are increasingly used to support early symptom recognition and care-seeking, yet evidence on their cost-effectiveness remains limited. We conducted an economic evaluation of a digital SC …

Published: March 2, 2026, midnight
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