Latest Articles

Role of soluble EGFR, Fas, and Fas ligand in pelvic pain severity and their association with endometriosis in infertile woman: a case-control study.

Endometriosis, a chronic inflammatory condition linked to pelvic pain and infertility, is characterized by immune dysfunction involving dysregulated apoptosis and cell proliferation. This case-control study included 87 infertile women undergoing …

Adenomyosis Pathophysiology, Diagnostic Advances, and Therapeutic Options.

Adenomyosis is a heterogeneous, nonmalignant uterine disorder characterized by ectopic endometrium within the myometrium, leading to abnormal uterine bleeding, dysmenorrhea, chronic pelvic pain, and subfertility. Once considered a disease of …

Synergistic effects of melatonin and dienogest on pain relief in endometriosis: a randomized controlled trial.

Endometriosis affects 5-10% of reproductive-aged women and is characterized by chronic pelvic pain, dysmenorrhea, dyspareunia, and infertility. Standard hormonal therapies, such as dienogest, effectively manage symptoms, but are often associated …

Risk Factors of Adolescent Endometriosis Onset and Recurrence: A Retrospective Study.

This study aimed to identify adolescent-specific risk factors for endometriosis onset and postoperative recurrence to facilitate early identification and risk stratification.

Understanding women's decisions to seek an endometriosis diagnosis: A Health Belief Model approach.

Early diagnosis of endometriosis is crucial, yet limited literature exists on factors influencing women's decisions to seek diagnosis. This study explores the role of symptoms, health beliefs, and social influences …

Medical Treatment for Endometriosis: One Size Does Not Fit All.

Endometriosis is associated with nociceptive pain, as well as peripheral and central sensitization. Evidence-based treatment suggestions for controlling endometriosis should be based on the convergence of the best scientific evidence, …

Diminished anticipatory pleasure predicts anhedonia in women with endometrisois: a case-control study.

Efficacy of probiotic supplementation in reducing primary dysmenorrhea: a double-blinded randomized controlled trial.

Primary dysmenorrhea is painful menstruation in the absence of pelvic pathology, whereas secondary dysmenorrhea is menstrual pain attributable to an underlying pelvic disease (e.g., endometriosis). Nonsteroidal anti-inflammatory drugs (NSAIDs) are …

Uterine Anteroposterior Diameter as an Imaging Correlate of Dysmenorrhea Severity: Findings Across Symptom Based Clusters.

Adenomyosis and endometriosis are both recognized as etiological factors in the development of dysmenorrhea; however, their respective contributions to this condition remains ambiguous. This study aims to examine the distinct …

International Clinical Practice Guidelines on Traditional Chinese Medicine Therapy for Dysmenorrhea: Development Protocol.

Traditional Chinese medicine (TCM) functions according to the concepts of "holism" and treatment based on syndrome differentiation, and it has achieved good clinical results in treating patients with dysmenorrhea, which …