There is currently no consensus on the etiology, pathogenesis, or treatment of endometriosis (EM). The discovery of disease-associated plasma proteins with causal genetic evidence provides an opportunity to identify new …
Infertility currently affects nearly one in six couples, representing more than 3.3 million people in France. Infertility now occurs in an unprecedented demographic context, marked by a rapid decline in fertility: …
We aimed to study the impact of centralizing surgical endometriosis care, including possible improvements in patient outcome.
The establishment of a successful pregnancy depends on proper embryo development and coordinated endometrial differentiation, particularly through the process of decidualization. Mesenchymal stem/stromal cells (MSCs), especially those derived from endometrial …
Endometriosis is associated with increased cardiovascular disease (CVD) risk, yet the cellular basis for this relationship remains unclear. We examined whether peritoneal fluid (PF) from women with endometriosis alters cardiomyocyte …
Endometriosis is a complex, multicompartmental disease in which accurately conveying the extent of involvement to the surgical team is essential for preoperative planning and patient counseling. In this context, medical …
Estrogen stimulates corticotropin-releasing hormone (CRH) expression in endometrial tissue, and CRH signaling contributes to inflammation and pain, suggesting a mechanistic role in endometriosis pathophysiology. We previously identified elevated CRH receptor-1 …
Women with endometriosis are at increased risk of preeclampsia and eclampsia, leading causes of maternal mortality among Black women in the United States. Despite this, Black women are significantly underdiagnosed …
Endometriosis (EMS) remains understudied in effective management strategies. The interplay between macrophage dysfunction and microbiota-derived immune signals emerges as a potential mechanism in EMS pathogenesis, suggesting its relevance for future …
Endometriosis and endometrial polyps are both estrogen-dependent conditions, and an association between these two pathologies has been observed in infertile women. Our research question was: "Is there an association between …