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Natural bioactive compounds and herbal medicines targeting common signaling pathways in endometriosis: mechanisms and therapeutic implications.

For a very long time, herbal treatments have served as remedies for various humans and animals. Natural compounds typically have multiple pharmacological actions because they interact with various biological targets. …

Published: Dec. 2, 2025, midnight
Association between the neutrophil percentage-to-albumin ratio and pelvic adhesion severity in endometriosis: A retrospective cross-sectional study.

Preoperative assessment of the severity of pelvic adhesions in endometriosis remains challenging. Inflammation may drive adhesion formation, and the predictive value of the neutrophil percentage-to-albumin ratio (NPAR, the ratio multiplied …

Published: Dec. 2, 2025, midnight
S1P3 Receptor Mediates the Proinflammatory Effect of the Endocannabinoid 2-Arachidonoylglycerol in Endometriotic Epithelial Cells.

Endometriosis is a chronic inflammatory disease characterized by the ectopic implantation of endometrium outside the uterus associated with pelvic pain and infertility. The molecular mechanisms involved in the pathogenesis of …

Published: Nov. 27, 2025, midnight
Risk of cardiovascular disease and mortality among women with endometriosis: A systematic review and meta-analysis.

Endometriosis is a chronic and estrogen-dependent disorder that affects about 10% of women of reproductive age worldwide. Endometriosis has been associated with chronic inflammation and an atherogenic lipid profile, two …

Published: Nov. 27, 2025, midnight
Molecular mechanısms of ovarian fibrosis.

Ovarian fibrosis is increasingly recognized as a pivotal factor contributing to ovarian aging, dysfunction and female infertility. It results from chronic or repetitive ovarian injury, such as that caused by …

Published: Nov. 26, 2025, midnight
Extracellular Trap-Related Genes as Potential Diagnostic Biomarkers for Endometriosis.

Endometriosis (EM), a prevalent gynecological disorder in reproductive-age women, lacks reliable noninvasive diagnostic tools. EM may be detected by neutrophil extracellular traps (NETs), which are essential to inflammation and immunological …

Published: Nov. 19, 2025, midnight
Could chronic inflammation be the medical paradigm shift of our age? - Aeon

Could chronic inflammation be the medical paradigm shift of our age? Aeon

Published: Nov. 18, 2025, 11:01 a.m.
The role of mitophagy in female reproductive system diseases: from molecular mechanisms to therapeutic strategies.

Mitophagy is a catabolic mechanism that selectively degrades damaged mitochondria and precisely modulates mitochondrial content, thereby maintaining intracellular homeostasis under stress conditions. To date, most reviews on mitophagy have predominantly …

Published: Nov. 18, 2025, midnight
''Non-Invasive Extracellular Vesicle Biomarkers in Endometriosis, Molecular Signatures Linking Pelvic Inflammation, Oocyte Quality, and IVF Outcomes''.

Endometriosis impairs fertility by interfering with ovarian function, embryonic development, and endometrial receptivity. Extracellular vesicles (EVs) are recognised as non-invasive biomarkers that may indicate biological processes based on their lipid, …

Published: Nov. 17, 2025, midnight
Impact of the lipid-inflammation axis on endometriosis risk: a multicenter case-control study using mediation analysis.

Endometriosis (EM) is often accompanied by dyslipidemia, but the causal relationship between dyslipidemia and inflammation remains unclear. This study aimed to explore the association between the lipid-inflammation axis and EM …

Published: Nov. 13, 2025, midnight
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