Latest Articles

Intraoperative Ultrasound for Localization of Deep Rectosigmoid Endometriosis Nodule.

The role of SYNE1/2 variants as a potential predisposition factor for the onset of endometriosis.

Endometriosis (EM) is a chronic, inflammatory gynaecological disorder defined by the presence of endometrial-like tissue outside the uterine cavity, most frequently affecting the ovaries, peritoneum, and uterosacral ligaments. Despite its …

Precise Surgical Navigation of Endometriosis via NIR-II Fluorescence Imaging With a Semiconducting Polymeric Probe.

Endometriosis is a prevalent gynecological disorder characterized by ectopic growth of endometrial-like tissue, often causing chronic pain, infertility, and systemic inflammation. Accurate detection and complete surgical resection remain challenging because …

Genetically predicted triglyceride levels and endometriosis risk: Mendelian randomization with exploratory multi-omics analyses.

This study explored the genetic evidence linking triglyceride-related pathways and lipid-lowering drug targets with endometriosis risk and investigated the genetic association between TG levels and EM. Using genome-wide association study …

Endometrial cells with high ALDH activity contribute to uterine development and regeneration.

Adult stem cells are thought to drive the regenerative potential of the endometrium and contribute to the pathogenesis of endometriosis; however, their identity and defining features remain to be characterized. …

Shared Genetic Architecture and Pleiotropic Loci Linking Endometriosis and Inflammatory Bowel Disease: An Integrative GWAS, Colocalization, and Mendelian Randomization Study.

Endometriosis (EMS) and inflammatory bowel disease (IBD) are both chronic inflammatory disorders with overlapping clinical features, suggesting a potentially shared etiology. Although epidemiological studies have reported an association between the …

Systems-level genomic analyses reveal shared mechanisms underlying endometriosis and sleep disorders.

We examined clinical, genetic, and molecular links between sleep disorders and endometriosis. Women aged 20-54 years in NHANES 2005-2006 were analyzed with survey-weighted logistic regression. Bidirectional two-sample Mendelian randomization (MR) …

Lower Urinary Tract Symptoms in Women with Surgically Confirmed Endometriosis: Association with Urethral Ultrasonographic Findings.

Background: Endometriosis is a chronic inflammatory disease affecting approximately 10% of women of reproductive age and is commonly associated with pelvic pain and infertility. Increasing evidence indicates that lower urinary …

Postoperative and long-term outcomes of nerve-sparing segmental rectal resection and complete nodular resection of rectal endometriosis.

Rectal endometriosis is a severe form of deep endometriosis affecting up to 12% of patients, causing significant pain and bowel dysfunction. The optimal surgical approach can be individually tailored based …

The effects of plasma protein levels on the risk of endometriosis: A Mendelian randomization study.

Endometriosis is a prevalent gynecologic disorder that significantly impacts women's health. However, its underlying pathogenesis remains unknown. This study aimed to ascertain causal associations between plasma protein levels and endometriosis …