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β-Glucuronidase at the gut-liver interface: Structural selectivity, enterohepatic reactivation, and the pharmacomicrobiomic case for precision inhibition.

β-Glucuronidase (β-G, EC 3.2.1.31) reverses phase II glucuronidation, and microbial β-G at the gut-liver interface reactivates biliary and circulating conjugates, closing enterohepatic loops for drugs, estrogens, bile acids, and bilirubin. …

Published: Sept. 9, 2026, midnight

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Antibody–drug conjugate Enterohepatic circulation Gut–liver axis Pharmacomicrobiomics Selective inhibition β-Glucuronidase

Effect of Goserelin acetate on non-invasive indices of hepatic steatosis in women with endometriosis.

Published: Dec. 29, 2025, midnight

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Fibrosis Goserelin Menopause Metabolic dysfunction-associated steatohepatitis Metabolic dysfunction-associated steatotic liver disease Non-invasive indices Nonalcoholic fatty liver disease Steatosis

Latest Articles

β-Glucuronidase at the gut-liver interface: Structural selectivity, enterohepatic reactivation, and the pharmacomicrobiomic case for precision inhibition.

Effect of Goserelin acetate on non-invasive indices of hepatic steatosis in women with endometriosis.

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